Do non-steroidal anti-inflammatory drugs cause exacerbations of inflammatory bowel disease?

Digestive Diseases and Sciences
Linda A Feagins, Byron L Cryer

Abstract

The safety of non-steroidal anti-inflammatory drugs (NSAIDs) in patients with inflammatory bowel disease (IBD) remains unclear. This report discusses potential mechanisms whereby NSAIDs might exacerbate IBD and reviews the available clinical data on the role of NSAIDs in causing exacerbations of ulcerative colitis (UC) and Crohn's disease (CD).

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