Do Oral Contraceptives Alter Knee Ligament Damage with Heavy Exercise?

The Tohoku Journal of Experimental Medicine
Haneul LeeJongEun Yim

Abstract

Hormones such as estradiol have an effect on human connective tissue, making women more susceptible to knee injuries. Indeed, women have a greater risk for non-contact injuries of anterior cruciate ligament (ACL) compared to men when participating in the same sports. The purpose of the present study was to examine the difference in ACL laxity after an eccentric exercise in the lower limbs in young healthy women between oral contraceptive pill (OCP) users and non-OCP users to see the effect of OCP on ACL laxity. Forty young healthy women participated in the experiments (25 with normal menstrual cycle and 15 with taking OCP). ACL laxity and a visual analog pain scale were measured before and after a bout of squat. OCP users had more pain than non-OCP users after heavy exercise (p < 0.001). Both groups showed a significant reduction in ACL laxity on the 2nd day after exercise (p < 0.05). While ACL laxity was always less in the OCP group, when expressed as a percent change from baseline, the ACL laxity change was similar in both groups (p > 0.05). We found that there was no statistically significant difference in ACL laxity recovery over time in response to the delayed onset muscle soreness after a bout of squat between two groups....Continue Reading

References

Jan 1, 1979·The American Journal of Sports Medicine·H E CabaudJ A Feagin
Nov 1, 1979·The American Journal of Sports Medicine·J A ArnoldW D Harris
Mar 1, 1991·The American Journal of Sports Medicine·F FlandryJ C Hughston
Jan 1, 1985·Rheumatology International·G B Langley, H Sheppeard
Sep 1, 1993·The American Journal of Sports Medicine·D L KowalkP Loubert
Jan 11, 2000·Clinical Orthopaedics and Related Research·W D YuG A Finerman
Jun 30, 2000·The Journal of the American Academy of Orthopaedic Surgeons·L Y GriffinE M Wojtys
Aug 10, 2002·Contraception·Kathleen J Savage, Priscilla M Clarkson
Sep 21, 2004·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Paul A MartineauMark L Burman
Sep 29, 2006·Sports Medicine·Bohdanna T ZazulakTimothy E Hewett
Aug 9, 2008·Journal of Applied Physiology·Glen P KennyOllie Jay
Aug 30, 2008·British Journal of Sports Medicine·S-K ParkJ L Ronsky
Sep 6, 2012·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Linda EkenrosCecilia Fridén
Oct 31, 2013·Journal of Clinical Medicine Research·Jerrold PetrofskyHaneul Lee
Apr 4, 2014·The Journal of Bone and Joint Surgery. American Volume·Sung-Jae KimMin Jung
Jul 10, 2014·International Orthopaedics·Andrea FerrettiIorio Raffaele

❮ Previous
Next ❯

Citations

Mar 16, 2018·The Tohoku Journal of Experimental Medicine·JongEun YimHaneul Lee
Nov 26, 2019·The American Journal of Sports Medicine·Jaclyn A KonopkaJason L Dragoo
Jan 31, 2019·Frontiers in Physiology·Nkechinyere Chidi-Ogbolu, Keith Baar

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.