Do out-of-pocket costs affect medication adherence in adults with rheumatoid arthritis? A systematic review

Seminars in Arthritis and Rheumatism
Parvaneh HeidariKimberley Crawford

Abstract

For individuals with a chronic condition, long-term management of their medication can be difficult and as a result non-adherence is common among this cohort. In patients with rheumatoid arthritis (RA), the introduction of biologic agents was a revolutionary treatment but the high costs of this medication might limit their utilisation. This systematic review aimed to determine whether out-of-pocket (OOP) costs affect adherence to RA medications in adults with a diagnosis of RA. Twelve databases were searched to identify primary peer-reviewed articles, written in English from inception to April 2016 that referred to the relationship between adherence to RA medication and OOP costs. The CASP check list was used to assess the quality rating of the included studies. Six articles were identified in the review and all were considered as high quality studies. Among them, three directly considered the association between OOP costs and medication adherence as their main objective. Although the population and the methods of the studies varied widely, there was an inverse relationship between OOP costs and medication adherence in patients with RA. The findings of this review suggest that OOP costs can contribute to non-adherence to RA med...Continue Reading

Citations

Mar 30, 2019·International Journal of Rheumatic Diseases·Parvaneh HeidariKimberley Crawford
Feb 12, 2020·PharmacoEconomics Open·Olivier HeinzlefJuliette Longin
Nov 30, 2020·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Morgane C MouslimJodi B Segal
Jan 5, 2021·Current Opinion in Rheumatology·Kevin Yip, Iris Navarro-Millán
Jul 19, 2020·Joint, Bone, Spine : Revue Du Rhumatisme·Jasvinder A SinghSusan M Goodman
Jun 15, 2021·Frontiers in Pharmacology·Shahin ShamsJudith F Ashouri
Sep 8, 2021·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·Friederike ThomasiusGeneviève Gauthier
Dec 28, 2021·Health & Social Care in the Community·Danielle BerkovicIlana N Ackerman

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