Do parents with an atopic family history adopt a 'prudent' lifestyle for their infant? (KOALA Study)

Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology
I KummelingP C Dagnelie

Abstract

Atopic parents may adopt lifestyle characteristics that allegedly protect against atopic disease. If this is true, infants from atopic parents will be characterized by low-risk behaviour. Consequently, aetiologic studies on lifestyle factors and allergic disease in childhood may be biased by confounding by indication. We explored whether the prevalence of 'prudent' lifestyle characteristics differs between atopic and non-atopic families. Information about a family history of atopic manifestations and lifestyle characteristics was collected by repeated questionnaires in the Dutch KOALA Birth Cohort Study in 2469 infants from families with divergent lifestyle practices (conventional vs. alternative). In conventional lifestyle families, infants were less often exposed to environmental tobacco smoke when parents were atopic than when they were non-atopic (10.0% vs. 14.7%, P=0.001). In alternative lifestyle families, exposure to smoking was very rare in both groups (1.7% vs. 2.6%). Pets were less often present in families with than without parental atopy (38.8% vs. 51.1%, P=0.008 for conventional lifestyle families; 43.0% vs. 48.4%, P=0.014 for alternative lifestyle families). Infants with atopic siblings had less often been vaccina...Continue Reading

References

Feb 1, 1994·American Journal of Respiratory and Critical Care Medicine·E von MutiusH H Thiemann
Jan 1, 1997·The European Respiratory Journal·P N Black, S Sharpe
Feb 1, 1997·The Journal of Allergy and Clinical Immunology·J N Baraniuk
Mar 1, 1997·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·D JarvisP Burney
Nov 5, 1997·Lancet·M R Sears
Jan 1, 1997·Epidemiologic Reviews·D L Duffy
Feb 13, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·E von Mutius
May 21, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·K WickensR Beasley
Oct 16, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·P A SteerenbergH Van Loveren
Jan 29, 2000·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·O S Von EhrensteinR von Kries
May 22, 2001·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A WijgaH J Neijens
Feb 18, 2003·The Journal of Allergy and Clinical Immunology·Adnan CustovicUNKNOWN National Asthma Campaign Manchester Asthma and Allergy Study Group
Jun 16, 2004·Journal of Clinical Epidemiology·C P van Schayck, J A Knottnerus
Jan 4, 2005·BMC Public Health·Janneke M BastiaanssenPiet A van den Brandt
Dec 14, 2005·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Ischa KummelingPiet A van den Brandt

❮ Previous
Next ❯

Citations

Nov 15, 2011·American Journal of Respiratory and Critical Care Medicine·Nilofar V FølsgaardHans Bisgaard
May 4, 2013·European Journal of Public Health·Ana Paula Simões-WüstCarel Thijs
Dec 7, 2007·The Journal of Allergy and Clinical Immunology·Robert J HancoxMalcolm R Sears
Jan 1, 2011·ISRN Allergy·Sofie StrømgaardVibeke Backer
Sep 11, 2014·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·E LavineM Ben-Shoshan

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.