PMID: 7012279Feb 1, 1981Paper

Do patients with demyelinating disease have antibodies against human glial cells in their sera?

Journal of Neurology, Neurosurgery, and Psychiatry
P G Kennedy, R P Lisak

Abstract

Cell-type-specific markers and indirect immunofluorescence were used to study immunoglobulin binding to glial cells in dissociated cell cultures of human foetal optic nerve, spinal cord and dorsal root ganglion in sera from patients with demyelinating diseases, other neurological diseases and normal controls. These various sera proved to be indistinguishable in that almost all of them contained immunoglobulin which bound weakly to all oligodendrocytes and fibroblasts, 5-25% of astrocytes and about 50% of Schwann cells.

References

Dec 1, 1977·The New England Journal of Medicine·O AbramskyD E Pleasure
Jul 1, 1979·Annals of Neurology·U TraugottC S Raine
Apr 1, 1966·Journal of Neurochemistry·W T Norton, L A Autilio

❮ Previous
Next ❯

Citations

Sep 1, 1983·Italian Journal of Neurological Sciences·R P LisakA J Summer
May 1, 1982·Journal of the Neurological Sciences·B Ryberg
Mar 1, 1988·Journal of the Neurological Sciences·B BrankinG B Wisdom
Mar 1, 1981·Journal of Neuroimmunology·H WattsM Thomas
Jan 1, 1983·Histopathology·D I GrahamI Brown
Jan 1, 1984·Annals of the New York Academy of Sciences·R P LisakD H Silberberg
Apr 1, 1982·Scottish Medical Journal·J A Simpson
Nov 1, 1996·Multiple Sclerosis : Clinical and Laboratory Research·R P Lisak

❮ Previous
Next ❯

Related Concepts

Related Feeds

Astrocytes

Astrocytes are glial cells that support the blood-brain barrier, facilitate neurotransmission, provide nutrients to neurons, and help repair damaged nervous tissues. Here is the latest research.