Do Pediatric Patients With Anterior Cruciate Ligament Tears Have a Higher Rate of Familial Anterior Cruciate Ligament Injury?

Orthopaedic Journal of Sports Medicine
Joshua T BramTheodore J Ganley

Abstract

Several studies have examined the anterior cruciate ligament (ACL) injury history among relatives of patients undergoing ACL reconstruction (ACLR), but they have primarily analyzed adults with variable results. We hypothesized that he rate of familial ACL injuries among pediatric patients with ACL tears would be greater than that among pediatric patients with uninjured knees. Cohort study; Level of evidence, 3. Pediatric patients (≤18 years of age) who underwent ACLR between January 2009 and May 2016 were contacted to complete a questionnaire on subsequent complications and family history of ACL tears. A control cohort was recruited from children with uninjured knees seen in the concussion clinic of our institution. Binary logistic regression was used to determine the factors predictive of having a familial ACL tear history or complications. Overall, 450 pediatric patients with primary ACL tears were included. Age at the time of surgery was 14.9 ± 2.2 years with a follow-up of 4.3 ± 2.1 years. When compared with 267 control patients, those with an ACL tear reported a higher rate of first-degree relatives with an ACL injury history (25.1% vs 12.0%; P < .001). In multivariate analysis, children with ACL injury had nearly 3 times ...Continue Reading

References

Nov 1, 1987·The American Journal of Sports Medicine·A F AndersonR B Addlestone
Jan 1, 1994·The American Journal of Sports Medicine·C D HarnerV C Cooley
Nov 22, 1997·Journal of Clinical Epidemiology·D A AschN A Christakis
Dec 22, 2004·The American Journal of Sports Medicine·R Kevin FlynnPeter J Fowler
May 25, 2005·The Journal of Bone and Joint Surgery. British Volume·R RameshP J Schranz
Aug 15, 2006·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Mark L BrandonMark F Sherman
Apr 3, 2008·Pediatrics·Stephen G Rice, UNKNOWN American Academy of Pediatrics Council on Sports Medicine and Fitness
Jun 10, 2008·British Journal of Sports Medicine·P RenstromL Engebretsen
Feb 6, 2009·British Journal of Sports Medicine·M PosthumusM Collins
Aug 8, 2012·The American Journal of Sports Medicine·Henry E BourkeLeo A Pinczewski
Oct 27, 2012·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Steven ClaesPeter Verdonk
Oct 4, 2013·The Journal of Bone and Joint Surgery. American Volume·Richard C MatherUNKNOWN MOON Knee Group
Jan 10, 2014·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Gregory D MyerTimothy E Hewett
Apr 15, 2014·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Maria WestinSuzanne Werner
Jul 13, 2014·The American Journal of Sports Medicine·Bruce D BeynnonRobert J Johnson
Dec 30, 2014·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·S L KeaysP A Newcombe
Dec 26, 2015·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Martin Hägglund, Markus Waldén
Feb 5, 2016·The American Journal of Sports Medicine·Rakesh JohnMohit Bhandari
Jun 9, 2016·The American Journal of Sports Medicine·Victoria L JohnsonDavid J Hunter
Nov 20, 2016·Current Opinion in Pediatrics·Meghan J PriceDaniel W Green
Jan 20, 2017·Sports Medicine·Mustafa KaynakDuncan E Meuffels
Feb 24, 2017·Pediatrics·Nicholas A BeckMarc Tompkins

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