Do periodontopathogens disappear after full-mouth tooth extraction?

Journal of Clinical Periodontology
Nele Van AsscheM Quirynen

Abstract

To monitor the intra-oral microbiological changes after full-mouth extraction using quantitative polymerase chain reaction (qPCR). Nine patients with severe, aggressive periodontitis, for whom a full-mouth tooth extraction was the only remaining treatment option were recruited. Before and 6 months after extraction, microbial samples were obtained (tongue, saliva and subgingival plaque) and analysed by qPCR. The elimination of subgingival niches, by extraction of all natural teeth, resulted in a 3-log reduction of Porphyromonas gingivalis and Tannerella forsythia, and more modest reductions of Aggregatibacter actinomycetemcomitans and Prevotella intermedia. However, the detection frequencies of these periodontopathogens in saliva and on the tongue remained unchanged after full-mouth tooth extraction. In contrast to what has been believed so far, full-mouth tooth extraction does not result in eradication of all periodontopathogens but only in a significant reduction. The clinical consequences of this observation remain speculative.

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Citations

Mar 1, 2012·Clinical Oral Investigations·Sigrun EickAnton Sculean
Sep 13, 2012·Implant Dentistry·Pablo Galindo-MorenoFrancisco O'Valle
Nov 3, 2010·Journal of Dental Research·N BuduneliD A Scott
Apr 2, 2011·Journal of Periodontology·Elena FigueroMariano Sanz
Jan 1, 2012·Microbial Ecology in Health and Disease·Justyna SutulaJoanna Verran
May 11, 2013·Journal of Periodontology·Yvonne C de WaalArie J van Winkelhoff
Feb 6, 2013·Journal of Clinical Periodontology·Yvonne C M de WaalEdwin G Winkel
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Dec 8, 2010·Periodontology 2000·Jørgen Slots, Henrik Slots
Jan 26, 2011·Journal of Periodontal Research·I SaygunJ Slots
Jun 28, 2012·Journal of Clinical Periodontology·Marco A PeresKaren G Peres
Mar 29, 2013·Journal of Clinical Periodontology·Stefan ReichertSusanne Schulz
Apr 15, 2011·Journal of Clinical Periodontology·Marc Quirynen, Nele Van Assche
Nov 9, 2010·Clinical Oral Implants Research·Ralph van BrakelWil van der Reijden
Nov 19, 2011·Clinical Oral Implants Research·M Quirynen, N Van Assche
Jul 30, 2014·Journal of Clinical Periodontology·Yvonne C M de WaalArie Jan van Winkelhoff
Apr 18, 2014·Periodontology 2000·Wim TeughelsMarc Quirynen
Jan 28, 2014·Journal of Clinical Periodontology·Aino SalminenPirkko J Pussinen
Sep 20, 2015·Clinical Oral Implants Research·Stefan Renvert, Marc Quirynen
May 12, 2015·Journal of Clinical Periodontology·Himabindu GogeneniÖzgün Özçaka
Jan 19, 2019·Oral Diseases·R Kyle GazdeckJoel L Schwartz
Sep 4, 2019·International Dental Journal·Jean-Louis GiovannoliGiovanni Serino
Jul 24, 2020·Clinical Advances in Periodontics·Maria L GeisingerNicolaas C Geurs

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