Do testicular seminoma and nonseminoma share the same etiology? Evidence from an age-period-cohort analysis of incidence trends in eight European countries

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology
Freddie BrayH Møller

Abstract

The incidence of the two main clinical subentities of testicular germ cell cancer (seminoma and nonseminoma) is increasing throughout Europe. Most studies have revealed little variation in risk factors between the two subtypes. This study compared generation-specific trends in eight European countries, hypothesizing that similar temporal pattern by birth cohort implied that seminoma and nonseminoma had a largely comparable etiology. The results are presented using the age-period-cohort model and the nonidentifiability problem highlighted by partitioning the age, period, and cohort effects in terms of their linear and curvature component parts, assuming a priori that cohort effects predominated. Despite uniform overall increases by calendar period, declining rates of nonseminoma but not pure seminoma were observed in the majority of countries during the 1990s. The subtype trends were, however, largely analogous on a birth cohort scale. Notable observations were a decline in rates of both subtypes among recent birth cohorts in Switzerland and a short-term wartime effect in several countries, involving an attenuation of increasing risk of both subtypes in men born in 1940 to 1945. Departures from the steady increases in testicular...Continue Reading

References

May 1, 1992·Cancer Causes & Control : CCC·A PrenerO M Jensen
Nov 1, 1989·Journal of the National Cancer Institute·H Møller
Jul 1, 1986·American Journal of Epidemiology·A R MossV Gurgin
Jul 1, 1987·British Journal of Cancer·M C PikeL G Bobrow
May 1, 1987·British Journal of Cancer·A J SwerdlowP G Smith
Jun 1, 1987·Statistics in Medicine·D Clayton, E Schifflers
Jun 1, 1987·Statistics in Medicine·D Clayton, E Schifflers
Jun 1, 1987·European Journal of Cancer & Clinical Oncology·P BoyleA G Robertson
Oct 1, 1994·International Journal of Cancer. Journal International Du Cancer·H O AdamiM Rahu
Mar 15, 1996·International Journal of Cancer. Journal International Du Cancer·T ZhengP Boyle
Jun 5, 1996·Journal of the National Cancer Institute·R BergströmT Hakulinen
Jul 3, 1996·Journal of the National Cancer Institute·O AkreH O Adami
Jan 14, 1998·Cancer Causes & Control : CCC·H Møller, N E Skakkebaek
Oct 16, 1999·International Journal of Cancer. Journal International Du Cancer·I dos Santos SilvaA Reid
Jul 18, 2000·International Journal of Cancer. Journal International Du Cancer·H K WeirL Sugar
Nov 26, 2002·International Journal of Cancer. Journal International Du Cancer·Eero Pukkala, Elisabete Weiderpass
Dec 20, 2002·Cancer·Katherine A McGlynnRobert E Tarone
Jan 28, 2004·Biostatistics·Tron A MogerSteinar Tretli
Mar 23, 2004·World Journal of Urology·K-P Dieckmann, U Pichlmeier
Mar 2, 2005·Nature Reviews. Cancer·J Wolter Oosterhuis, Leendert H J Looijenga
Apr 9, 2005·International Journal of Cancer. Journal International Du Cancer·Michael J GarnerDaniel Krewski

❮ Previous
Next ❯

Citations

Feb 1, 2008·Cancer Causes & Control : CCC·Marie WalschaertsPatrick Thonneau
May 15, 2008·Cancer Causes & Control : CCC·Peter BaadeL Fritschi
Apr 24, 2013·Nature Reviews. Urology·Mausam Singhera, Robert Huddart
Dec 19, 2009·Annals of Oncology : Official Journal of the European Society for Medical Oncology·K HemminkiJ Sundquist
May 8, 2010·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Victoria M ChiaKatherine A McGlynn
May 26, 2011·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Philip S Rosenberg, William F Anderson
Oct 16, 2012·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Philip S RosenbergWilliam F Anderson
May 17, 2011·Hematology/oncology Clinics of North America·Andreas Stang, Oliver Kuss
May 21, 2010·Urologic Oncology·Hao LiuKari Hemminki
Feb 11, 2009·Cancer·Janet R DalingStephen M Schwartz
Sep 11, 2012·International Journal of Cancer. Journal International Du Cancer·Hagai LevineJeremy D Kark
Jul 29, 2008·International Journal of Andrology·M B CookK A McGlynn
Mar 9, 2010·Statistics in Medicine·Philip S Rosenberg, William F Anderson
Feb 18, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Abu Bakar Hafeez BhattiKhurram Mir
Nov 13, 2014·Cancer Causes & Control : CCC·Ariana ZnaorFreddie Bray
May 29, 2016·Cancer Epidemiology·Marina T van LeeuwenClaire M Vajdic
Dec 29, 2013·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Charlotte Le CornetFreddie Bray
Dec 30, 2008·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Sandra SesekeFlorian Seseke
Dec 26, 2008·European Journal of Epidemiology·Andreas Stang
Jun 18, 2009·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Hadriano M LacerdaLorenzo Richiardi
Sep 21, 2006·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Andreas Stang, Karl-Heinz Jöckel
Aug 26, 2014·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Philip S RosenbergWilliam F Anderson
Apr 1, 2010·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Omid BeikiTahereh Moradi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

International Journal of Cancer. Journal International Du Cancer
Mark P PurdueKatherine A McGlynn
Nature Reviews. Cancer
J Wolter Oosterhuis, Leendert H J Looijenga
© 2022 Meta ULC. All rights reserved