Do topical nasal decongestants affect polyps?

Acta Oto-laryngologica
Leif JohanssonMats Bende

Abstract

The hypothesis that decongestants reduce the size of nasal polyps could not be verified. Decongestion is therefore recommended prior to nasal endoscopy, especially in polyp diagnosis, as it does not artificially change the size of the polyps. The role of nasal decongestants in nasal stuffiness is well established and their action is well known. Decongestants are also used prior to nasal endoscopy to achieve a better view of the nasal cavity in order to diagnose polyps. The question is whether this decongestion invalidates the estimation of polyp size in clinical and scientific practice. The aim of this study was to evaluate possible effects of topical decongestants on polyp extension in patients with nasal polyposis. The effect of the decongestants nafazoline and epinephrine on nasal polyp size was assessed by means of a double-blind, placebo-controlled randomized study. A sensitive endoscopic scoring system, lateral imaging, was used to assess the size and extension of the nasal polyps. No significant effect of decongestion on polyp size could be found for either treatment.

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Citations

Jan 26, 2012·Current Allergy and Asthma Reports·Isam Alobid, Joaquim Mullol
Feb 22, 2012·Current Allergy and Asthma Reports·Jochen G Mainz, Assen Koitschev
Jun 21, 2013·International Journal of General Medicine·Patorn PiromchaiSanguansak Thanaviratananich
Jul 28, 2010·Expert Review of Respiratory Medicine·José Maria GuilemanyJoaquim Mullol
Dec 22, 2011·American Journal of Rhinology & Allergy·Rony K Aouad, Alexander G Chiu
Feb 6, 2021·Revue des maladies respiratoires·S BartierE Bequignon
Jul 16, 2021·The Journal of Allergy and Clinical Immunology. in Practice·Nicholas James CampionVerena Niederberger-Leppin

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