Do ultrasonic contrast agents artificially increase maximum Doppler shift? In vivo study of human common carotid arteries

Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine
M GutberletR Felix

Abstract

The aim of this study was to establish whether an increase of maximum Doppler shift occurs in the human common carotid artery after the administration of Levovist, an ultrasonographic echo enhancer. Twenty common carotid arteries of 10 patients were examined. Spectral Doppler waveform examinations were performed before and after administration of Levovist using an Acuson 128 XP 10 and a 7.0 MHz transducer probe. Time averaged mean velocity, peak velocity, maximum Doppler shift, and spectral Doppler indices (pulsatility index, resistive index, systolic-diastolic ratio) were assessed. No significant changes in any of the measured parameters, including maximum Doppler shifts, peak velocity (P = 0.35, Wilcoxon rank sum test), pulsatility indices (P = 0.70), resistive indices (P = 0.98), or other spectral indices, were found. We conclude that an increase in Doppler shift does not inevitably occur after the administration of a signal enhancer when examining the human common carotid artery.

Citations

Dec 5, 2017·Abdominal Radiology·David T FetzerRichard G Barr
Apr 27, 2001·Journal of Clinical Ultrasound : JCU·A J LemkeR Felix
Jul 4, 2017·Clinical and Molecular Hepatology·Young Seo ChoDagvasumberel Munkhbaatar
Nov 2, 2019·Ultrasonography·Vasileios RafailidisPaul S Sidhu
Nov 5, 1999·Stroke; a Journal of Cerebral Circulation·D W DrosteE B Ringelstein
Sep 19, 2000·Radiographics : a Review Publication of the Radiological Society of North America, Inc·G SoulezE Therasse

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