Do unusual site-specific population dynamics of rodent reservoirs provide clues to the natural history of hantaviruses?

Journal of Wildlife Diseases
Charles H CalisherBarry J Beaty

Abstract

Between January 1995 and November 1997, longitudinal mark-recapture studies of rodent hosts of hantaviruses in a disturbed microhabitat within a shortgrass prairie ecosystem in southeastern Colorado (USA) were conducted. The site was distinguished by edaphic and floristic characteristics unique to this area and associated with historical land use patterns, as well as the year-around availability of water from a functioning windmill. Populations of two common rodent species that are hosts for hantaviruses, Peromyscus maniculatus and Reithrodontomys megalotis, had unusually rapid turnover, a younger age structure, and a much lower prevalence of antibody to Sin Nombre virus than did populations at nearby sites in more typical shortgrass prairie and canyon habitats. Based on these findings, we suggest that a stable resident population of the reservoir is critical to the maintenance of hantaviruses at a given site, and we hypothesize that long-lived, persistently infected rodents are the principal transseasonal reservoir of hantaviruses.

Citations

Aug 19, 2007·Bulletin of Mathematical Biology·Frederick R AdlerM Denise Dearing
Jan 9, 2009·Proceedings. Biological Sciences·Christine A ClayM Denise Dearing
Dec 11, 2002·Proceedings of the National Academy of Sciences of the United States of America·Gregory E GlassJames N Mills
Jul 30, 2014·Vector Borne and Zoonotic Diseases·Hussein KhalilFrauke Ecke
Feb 23, 2010·Infectious Disease Clinics of North America·Steven Q SimpsonIbrahim Faruqi
Jun 12, 2010·Annals of the New York Academy of Sciences·M Denise Dearing, Laurie Dizney
Feb 1, 2017·Annual Review of Entomology·Charles H Calisher
Jan 31, 2003·Journal of the American Veterinary Medical Association·Charles H CalisherBarry J Beaty
May 2, 2018·EcoHealth·Matthew T MilhollandJames N Mills
Jun 18, 2017·EcoHealth·Paula Ribeiro PristJean Paul Metzger

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