Do we know how best to disinfect child care sites in the United States? A review of available disinfectant efficacy data and health risks of the major disinfectant classes

American Journal of Infection Control
Stephanie M HolmMark D Miller

Abstract

Children in child care settings have a high infectious burden. They are frequently exposed to sanitizing and disinfecting agents, whose toxicities have not been studied in these settings. Current guidance on the preferred disinfection agents for child care is vague. This article combines 2 different sources of information: the Environmental Protection Agency registration data on the efficacy of hospital-grade disinfectants and a review of the research on the toxicities of the most common of these disinfectants to summarize information that could be used for more evidence-based early care and education disinfection regulations and guidelines. Coverage of these organisms varied both between disinfectant classes (defined by active ingredient), as well as within classes. The 3 most common active ingredients in the database-quaternary ammonias, bleaches, and hydrogen peroxides-had 251, 63, and 31 products, respectively. Quaternary ammonias and bleaches are both known asthmagens, with the potential for toxic gas release when mixed. Quaternary ammonias may also cause reproductive toxicity. Disinfectant-grade peroxides have relatively low inhalational toxicity. A clear rationale is needed to establish policies for determining preferabl...Continue Reading

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Citations

Mar 20, 2021·American Journal of Infection Control·Jennifer Sanguinet, Charles Edmiston
Jun 3, 2021·International Journal of Environmental Research and Public Health·Brenda D KoesterLeona Yi-Fan Su
Aug 28, 2021·International Journal of Environmental Research and Public Health·Cassandra D QuerdibittyAlicia L Salvatore
Aug 30, 2021·American Journal of Infection Control·Timothy J HilbertErin N Haynes
Jun 23, 2020·American Journal of Infection Control·John M Boyce

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