Do we need a new CT scan for retreatment of intracranial SRS patients?

Journal of Applied Clinical Medical Physics
David WiantBenjamin Sintay

Abstract

To determine if the treatment planning computed tomography scan (CT) from an initial intracranial stereotactic radiosurgery (SRS) treatment can be used for repeat courses of SRS. Twenty-five patients with 40 brain metastases that received multiple courses of SRS were retrospectively studied. Magnetic resonance scans from repeat SRS (rMR) courses were registered to CT scans from the initial SRS (iCT) and repeat SRS (rCT). The CT scans were then registered to find the displacement of the rMR between iCT and rCT registrations. The distance from each target to proximal skull surface was measured in 16 directions on each CT scan after registration. The mutual information (MI) coefficients from the registration process were used to evaluate image set similarity. Targets and plans from the rCTs were transferred to the iCTs, and doses were recalculated on the iCT for repeat plans. The two dose distributions were compared through 3D gamma analysis. The magnitude of the mean linear translations from the MR registrations was 0.6 ± 0.3 mm. The mean differences in distance from target to skull on a per target basis were 0.3 ± 0.2 mm. The MI was 0.582 ± 0.042. Registration between a comparison group of 30 CT scans that had the same data resa...Continue Reading

References

Jun 3, 1998·Medical Physics·D A LowJ A Purdy
Oct 17, 2001·Journal of Applied Clinical Medical Physics·J Vaarkamp
Aug 23, 2005·International Journal of Radiation Oncology, Biology, Physics·Minesh P MehtaLuis Souhami
Apr 13, 2010·International Journal of Radiation Oncology, Biology, Physics·Kenneth UlinJoel M Cherlow
Jul 23, 2011·Medical Physics·Adam JohanssonTufve Nyholm
Jan 8, 2015·Physics in Medicine and Biology·J SjölundH Knutsson
Oct 16, 2015·International Journal of Radiation Oncology, Biology, Physics·Weili ZhengCarri K Glide-Hurst
Nov 20, 2015·International Journal of Radiation Oncology, Biology, Physics·Eric ParadisJames M Balter
Mar 31, 2016·Practical Radiation Oncology·David WiantBenjamin Sintay
May 23, 2016·International Journal of Radiation Oncology, Biology, Physics·Ryan G PriceCarri Glide-Hurst

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Citations

Feb 28, 2019·Critical Care : the Official Journal of the Critical Care Forum·Sangkil LeeJeong-Am Ryu

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Software Mentioned

iPlan
MIM
GammaPlan
MIM Maestro
Brainlab iPlan
Varian Eclipse
Matlab

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