Do we need to shift from dye injection to fluorescence in respective liver surgery?

Surgical Oncology
Nobuyuki Takemura, N Kokudo

Abstract

Anatomical hepatectomy for hepatocellular carcinoma (HCC) has been a standard procedure for hepatic surgeons by guaranteeing curability and hepatic parenchymal preservation. Recently, indocyanine green (ICG) fluorescent imaging has been applied for hepatobiliary surgery, in substitution for cholangiography, to detect hepatic tumors, and the anatomical hepatectomy. This technique can reveal the hepatic segmental border line on the hepatic surface and its boundary plane during hepatic parenchymal resection. Initially, dye staining with indigo-carmine has been used for anatomical hepatectomy, and recently, ICG fluorescent imaging is applied to this technique. The conventional dye staining method is an innovative method for indicate the hepatic segmental border on the hepatic surface that can otherwise never be visualized. However, the intensity of staining is inconsistent or skill-dependent and disappears quickly with dilution because it is not taken up by the liver. The advantages of ICG fluorescent segmental staining are its high reproducibility and sensitivity. It stays in the injected segment for a few hours because ICG is taken up by hepatocytes. The segmental border inside the liver can also be visualized by this technique, ...Continue Reading

Related Concepts

Related Feeds

Carcinoma, Hepatocellular

Hepatocellular Carcinoma is a malignant cancer in liver epithelial cells. Discover the latest research on Hepatocellular Carcinoma here.

Adrenocortical Carcinoma

Hepatocellular carcinoma is the most common type of primary liver cancer and frequently occurs in individuals with chronic liver diseases like cirrhosis. Here is the latest research.