Do we treat the male or his gamete?

Human Reproduction
P DevroeyA C Van Steirteghem

Abstract

The history of the male infertility patient is of utmost value. A physical examination is mandatory when psychosexual and ejaculatory dysfunction and male accessory gland infection are suspected, and even in the presence of azoospermia. It is also advisable to perform a physical examination to exclude the presence of testicular tumours. The diagnostic assessment includes sperm analysis, history, physical examination, the Valsalva manoeuvre, Doppler, ultrasonography, hormonal serum measurements, evaluation of testicular volume by orchidometry and evaluation of testicular consistency by palpation. The diagnosis of male infertility is descriptive and determination of true causality is almost non-existent. For decades, various therapies have been proposed to improve sperm parameters in cases of male factor infertility. Administration of anti-oestrogens and androgens is ineffective. No peer-review data are available to demonstrate the benefit of the use of intrauterine insemination or the correction of varicocele. Classic in-vitro fertilization is to some extent a solution for male factor infertility; however, the two-pronuclear fertilization rate for patients with impaired semen samples is significantly lower than that for patients...Continue Reading

Citations

Jul 4, 2002·Fertility and Sterility·Sjoerd ReppingFulco van der Veen
May 30, 2003·Biology of Reproduction·Jakob O GjørretPoul Maddox-Hyttel
May 29, 2002·Current Opinion in Obstetrics & Gynecology·Mohamed F Mitwally, Robert F Casper
Jan 11, 2000·Clinical Obstetrics and Gynecology·S J Silber
Jun 28, 2011·Fertility and Sterility·Sherman J Silber
Jun 23, 2009·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Marcia C Inhorn
Jul 4, 2001·The Journal of Urology·P N Kolettis, E S Sabanegh
Mar 29, 2018·Journal of Assisted Reproduction and Genetics·Sherman Silber

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