Do We Utilize Our Knowledge of the Skin Protective Effects of Carotenoids Enough?

Antioxidants
Anamaria Balić, Mislav Mokos

Abstract

Due to their potential health-promoting effects, carotenoids have drawn both scientific and public attention in recent years. The primary source of carotenoids in the human skin is diet, mainly fruits, vegetables, and marine product, but they may originate from supplementation and topical application, too. In the skin, they accumulate mostly in the epidermis and act as a protective barrier to various environmental influences. Namely, the skin is exposed to numerous environmental factors, including ultraviolet radiation (UVR), air pollution, and smoking, that cause oxidative stress within the skin with consequent premature (extrinsic) aging. UVR, as the most prominent environmental factor, may cause additional detrimental skin effects, such as sunburn, DNA damage, and skin cancer. Therefore, photoprotection is the first line intervention in the prevention of premature aging and skin cancer. Numerous studies have demonstrated that carotenoids, particularly β-carotene, lycopene, lutein, and astaxanthin, have photoprotective effects, not only through direct light-absorbing properties, but also through their antioxidant effects (scavenging reactive oxygen species), as well as by regulation of UV light-induced gene expression, modula...Continue Reading

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Citations

Sep 11, 2020·European Journal of Nutrition·Kyoko MiuraAdèle C Green
Nov 2, 2019·Antioxidants·Volker Böhm
May 20, 2020·International Journal of Molecular Sciences·Elena Di Pierro, Francesca Granata
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Jul 3, 2021·Antioxidants·Luciana de Souza GuedesAndré Rolim Baby
Jun 1, 2021·Nutrition Research Reviews·Torsten BohnJoanna Dulińska-Litewka

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Methods Mentioned

BETA
biopsies
environmental stress

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