PMID: 7993151Dec 12, 1994Paper

Dobutamine-atropine stress echocardiography in elderly patients unable to perform an exercise test. Hemodynamic characteristics, safety, and prognostic value

Archives of Internal Medicine
D PoldermansJ R Roelandt

Abstract

To establish the hemodynamic effects, safety, and prognostic value of dobutamine-atropine stress echocardiography in patients 70 years of age or older. Observational study at a university hospital. One hundred seventy-nine patients (mean age, 75 years; range, 70 to 90 years) referred for chest pain (n = 73) or preoperative risk assessment for major vascular noncardiac surgery (n = 106). All patients underwent clinical evaluation and dobutamine-atropine stress test. One hundred seventy-nine stress tests were performed. Test end points were the target heart rate (85% of theoretical maximum heart rate), reached in 165 tests (92%); inadequate echo images, two tests (1%); and side effects, 12 tests (7%). Side effects that caused a premature end of the test were severe chest pain (n = 5 [2.8%]), electrocardiographic changes (n = 1 [0.6%]), hypotension (n = 2 [1.1%]), chills (n = 2 [1.1%]), and cardiac arrhythmias (paroxysmal atrial fibrillation) (n = 2 [1.1%]). New wall motion abnormalities as a marker of myocardial ischemia occurred in 50 tests (28%). No death or myocardial infarction occurred during the test. Perioperative events occurred in 12 patients (four cardiac deaths, three myocardial infarctions, and five episodes of unstab...Continue Reading

Citations

Sep 14, 2014·Progress in Cardiovascular Diseases·Nidhi MehtaJames N Kirkpatrick
Nov 12, 2005·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Elena BiaginiDon Poldermans
Jun 26, 2012·Expert Opinion on Drug Safety·Juan TamargoEva Delpón
Aug 2, 2006·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Sergio L KobalRobert J Siegel
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Aug 12, 2005·Current Opinion in Cardiology·Elena BiaginiDon Poldermans
Jul 1, 2010·The International Journal of Cardiovascular Imaging·Francesca InnocentiRiccardo Pini

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