PMID: 11907003Mar 22, 2002Paper

Dobutamine stress echocardiography for the detection of myocardial viability in patients with left ventricular dysfunction taking beta blockers: accuracy and optimal dose

Heart
T ZaglavaraA Kenny

Abstract

To assess the accuracy of dobutamine stress echocardiography (DSE) and the optimal dose of dobutamine to detect myocardial viability in patients with ischaemic left ventricular (LV) dysfunction who are taking beta blockers, using the recovery of function six months artery revascularisation as the benchmark. 17 patients with ischaemic LV dysfunction (ejection fraction < 40%) and chronic treatment with beta blockers scheduled to undergo surgical revascularisation. Regional cardiothoracic centre. All patients underwent DSE one week before and resting echocardiography six months after revascularisation. A wall motion score was assigned to each segment for each dobutamine infusion stage, using the standard 16 segment model of the left ventricle. The accuracy of DSE to predict recovery of resting segmental function was calculated for low dose (5 and 10 microg/kg/min) and for a full protocol of dobutamine infusion (5 to 40 microg/kg/min). Of the 272 segments studied, 158 (58%) were dysfunctional at rest, of which 79 (50%) improved at DSE and 74 (47%) recovered resting function after revascularisation. Analysis of results with a low dose showed a significantly lower sensitivity and negative predictive value than with a full protocol (4...Continue Reading

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Sep 8, 1999·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·T ZaglavaraA Kenny
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Jan 3, 2001·American Heart Journal·J B ShammashS E Kimmel

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Citations

Apr 1, 1994·Journal of the American College of Cardiology·M OstojicM Nedeljkovic
Dec 15, 2006·European Journal of Heart Failure·Stefanos E KaragiannisDon Poldermans
Feb 28, 2006·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Theodora ZaglavaraAntoinette Kenny
Feb 16, 2020·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Ahsan Javed, Krishna S Nayak
Feb 26, 2008·British Journal of Hospital Medicine·N R BannerS Rahman-Haley

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