Dobutamine stress echocardiography in the diagnosis of asymptomatic ischemic heart disease in patients with chronic kidney disease--review of literature and single-center experience

Transplantation Proceedings
B Januszko-GiergielewiczB Rutkowski

Abstract

Coronary artery disease (CAD) may be present in kidney transplant (KT) candidates without the presence of CAD clinical symptoms. This study joins an ongoing discussion about appropriate noninvasive diagnostic approaches for ischemic heart disease (IHD) assessment and patient selection for revascularization procedures. The aim of this study was to evaluate the role of dobutamine stress echocardiography (DSE) in IHD diagnosis in initially asymptomatic maintenance hemodialysis (HD) patients. Forty HD patients aged 52.4 ± 2.0 years, were studied for 2.5 years. At inclusion, they were free of both symptoms and history of IHD. Standard electrocardiography (ECG), chest X-ray, standard echocardiography, DSE, 24-hour Holter ECG, and Doppler ultrasonography (carotids and lower extremities) were performed. Results were analyzed according to a predefined diagnostic algorithm. DSE yielded negative results in all patients. Left ventricular (LV) ejection fraction ≤ 60%, LV hypertrophy, and Holter ECG silent ischemia features were noticed in 15%, 70%, and 10% of patients, respectively. Atherosclerotic lesions in lower extremities and carotid arteries were present in 50% and 37.5% of patients, respectively. During the follow-up, 9/40 patients d...Continue Reading

References

Jun 1, 1996·American Heart Journal·S AbeG Sloman
May 1, 1997·Progress in Cardiovascular Diseases·W F Armstrong
Jul 3, 2002·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·T JogestrandUNKNOWN Swedish Quality Board for Carotid Surgery
Oct 8, 2005·Transplantation·Bertram L KasiskeCharles A Herzog
Dec 19, 2009·Transplantation·José Jayme G De LimaEduardo M Krieger

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Citations

Nov 23, 2018·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·R Brandon StaceyW Gregory Hundley
Apr 24, 2019·Medicina·Beata Januszko-GiergielewiczAlicja Dębska-Ślizień

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