Does 18F-FDG PET/MRI reduce the number of indeterminate abdominal incidentalomas compared with 18F-FDG PET/CT?

Nuclear Medicine Communications
Benedikt M SchaarschmidtChristian Buchbender

Abstract

Incidental masses of abdominal organs are a relevant problem in radiological examinations. The aim of this study was to evaluate whether simultaneous (18)F-fluorodeoxyglucose ((18)F-FDG) PET/MRI, because of its higher soft-tissue contrast and the diversity of available pulse sequences, can reduce the number of indeterminate abdominal incidentalomas compared with (18)F-FDG PET/computed tomography (CT). In this retrospective study, we enrolled 173 patients (91 women and 82 men, mean age 55.8±14.6 years) who underwent contrast-enhanced (18)F-FDG PET/CT on the same day for oncological indications. Data sets were examined in a random order by two readers noting incidentalomas and incidental tracer uptake of the liver, kidneys, spleen, pancreas, adrenal glands, and gallbladder. Findings were categorized into three categories: most likely malignant, indeterminate, and most likely benign. In addition, the most relevant MR sequence for the final decision was recorded for each incidentaloma. The numbers of benign, indeterminate, and malignant findings on (18)F-FDG PET/CT and (18)F-FDG PET/MRI were compared. A subgroup analysis was carried out to detect potential differences with respect to lesion location (organwise) and lesion consisten...Continue Reading

References

Nov 1, 1992·Radiology·D G MitchellM M Miettinen
Sep 27, 2003·Radiology·Gerald AntochLutz S Freudenberg
Oct 30, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Gerald AntochLutz S Freudenberg
Nov 10, 2004·Journal of Digital Imaging·Antoine RossetOsman Ratib
Jul 26, 2005·Radiology·Gary M Israel, Morton A Bosniak
Sep 20, 2005·Radiology·Claudia D FurtadoGiovanna Casola
Sep 18, 2008·Radiology·Stuart G SilvermanJerome P Richie
Oct 5, 2010·Journal of the American College of Radiology : JACR·Lincoln L BerlandAndrew J Taylor
May 15, 2012·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Christian BuchbenderGerald Antoch
Jul 12, 2012·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Christian BuchbenderGerald Antoch
Feb 15, 2013·Nuclear Medicine Communications·Ronnie SebroMiguel Hernandez Pampaloni
Sep 10, 2013·European Journal of Radiology·Karsten BeiderwellenThomas C Lauenstein
Dec 3, 2013·European Journal of Nuclear Medicine and Molecular Imaging·K KubiessaP Stumpp
Feb 8, 2014·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Philipp HeuschTill A Heusner
Feb 13, 2014·Abdominal Imaging·William E SchaafLester S Johnson
Aug 13, 2014·European Journal of Nuclear Medicine and Molecular Imaging·Philipp HeuschChristian Buchbender

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Citations

Nov 3, 2015·Academic Radiology·Tyler J FraumJonathan McConathy
Jul 18, 2016·Revista española de medicina nuclear e imagen molecular·C Riola-ParadaJ L Carreras-Delgado
Jun 18, 2020·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Dong ZhengJiahe Tian
Mar 3, 2017·Nuclear Medicine and Molecular Imaging·Hyun Woo KwonGi Jeong Cheon
Dec 21, 2016·Nuclear Medicine and Molecular Imaging·Tyler J FraumFarrokh Dehdashti
Dec 7, 2019·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Ole MartinLale Umutlu
Oct 2, 2021·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Samuel J GalganoJonathan E McConathy

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