Does AMH Reflect Follicle Number Similarly in Women with and without PCOS?

PloS One
Sverre C ChristiansenSven M Carlsen

Abstract

Increased Anti-Mullerian Hormone in polycystic ovary syndrome, may be due to overactive follicles rather than reflect antral follicle count. Does Anti-Mullerian Hormone reflect antral follicle count similarly in women with or without polycystic ovary syndrome or polycystic ovarian morphology? Cross-sectional, case-control. Women who delivered preterm in 1999-2006. For each index woman, a woman with a term delivery was identified. Participation rate was 69%. Between 2006-2008, 262 women were included, and diagnosed to have polycystic ovary syndrome, polycystic ovarian morphology or to be normal controls. Blood tests, a clinical examination and vaginal ultrasound. Anti-Mullerian Hormone / antral follicle count -ratio, SHBG, androstenedione and insulin, to test potential influence on the Anti-Mullerian Hormone / antral follicle count -ratio. Mean Anti-Mullerian Hormone / antral follicle count ratio in women with polycystic ovary syndrome or polycystic ovarian morphology was similar to that of the controls (polycystic ovary syndrome: 1,2 p = 0,10 polycystic ovarian morphology: 1,2, p = 0,27 Controls 1,3). Anti-Mullerian Hormone showed a positive linear correlation to antral follicle count in all groups. Multivariate analysis did no...Continue Reading

References

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Citations

Mar 24, 2018·Nature Reviews. Endocrinology·Héctor F Escobar-Morreale
Nov 7, 2017·Climacteric : the Journal of the International Menopause Society·S MinooeeF Azizi
Jun 1, 2018·Clinical Endocrinology·Inthrani R IndranEu Leong Yong
Apr 4, 2017·The Journal of Clinical Endocrinology and Metabolism·Catherine M GordonMichelle P Warren
Sep 26, 2017·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·M StracquadanioM A Palumbo
Mar 11, 2021·PloS One·Agnieszka ŻelaźniewiczBogusław Pawłowski

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Methods Mentioned

BETA
blood drawing
blood draw
enzyme-linked immunosorbent assay
ELISA
contraception

Software Mentioned

SPSS
PASW

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