Does blood of healthy subjects contain bacterial ribosomal DNA?

Journal of Clinical Microbiology
Simo NikkariD A Relman

Abstract

Real-time PCR methods with primers and a probe targeting conserved regions of the bacterial 16S ribosomal DNA (rDNA) revealed a larger amount of rDNA in blood specimens from healthy individuals than in matched reagent controls. However, the origins and identities of these blood-associated bacterial rDNA sequences remain obscure.

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