Does cardiorespiratory fitness moderate the prospective association between physical activity and cardiometabolic risk factors in children?

International Journal of Obesity : Journal of the International Association for the Study of Obesity
T SkredeUlf Ekelund

Abstract

Physical activity (PA) and cardiorespiratory fitness (CRF) are independently associated with reduced cardiometabolic risk in children, and may affect risk through different pathways. This study aims to examine if CRF moderate the prospective association between PA, sedentary time, and cardiometabolic outcomes in 10-year-old children. In total, 718 children of 1129 (drop out n = 7) had valid measures of PA (accelerometry), CRF (the Andersen running test), and a cardiometabolic risk profile measured at baseline and follow-up 7 months later. Cardiometabolic outcomes were systolic blood pressure, waist circumference (WC), total cholesterol, high-density lipoprotein, triglycerides, glucose, and insulin (HOMA-IR). The cardiometabolic risk factors were analysed individually, and as a clustered risk score (z score). A linear mixed model was used to examine the prospective associations between different PA exposures (overall PA, sedentary time, moderate-to-vigorous PA (MVPA), vigorous PA) and cardiometabolic outcomes, including the interaction term PA × CRF in the model to assess moderation by CRF. CRF modified the association for baseline overall PA (P < 0.039) and MVPA (min/day) with clustered cardiometabolic risk at follow-up (P < 0....Continue Reading

References

Dec 1, 1981·The Journal of Clinical Investigation·R A DeFronzoJ Wahren
Mar 24, 1998·Annual Review of Medicine·L J Goodyear, B B Kahn
May 16, 1998·BMJ : British Medical Journal·T V Perneger
Dec 22, 1998·The American Journal of Cardiology·G S BerensonT A Nicklas
Sep 22, 1999·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·M A FergusonS Owens
Jun 28, 2001·Medicine and Science in Sports and Exercise·C Bouchard, T Rankinen
Nov 6, 2003·JAMA : the Journal of the American Medical Association·Olli T RaitakariJorma S A Viikari
Nov 19, 2005·Medicine and Science in Sports and Exercise·Stewart G TrostRussell R Pate
Jun 10, 2006·Journal of Applied Physiology·Giorgos N KraniouMark Hargreaves
Apr 7, 2007·Medicine and Science in Sports and Exercise·Calum MattocksChris Riddoch
Aug 2, 2007·European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology·Sigmund A AnderssenLars B Andersen
May 30, 2008·The New England Journal of Medicine·Jean-Claude Carel, Juliane Léger
Oct 25, 2008·Journal of Sports Sciences·Kelly R EvensonRobert G McMurray
Jun 25, 2010·BMJ : British Medical Journal·Jennifer A HutcheonJames A Hanley
Dec 7, 2010·Medicine and Science in Sports and Exercise·Stewart G TrostKarin A Pfeiffer
May 31, 2011·BMJ : British Medical Journal·Philippa J CarterRachael W Taylor
Feb 18, 2012·JAMA : the Journal of the American Medical Association·Ulf EkelundUNKNOWN International Children's Accelerometry Database (ICAD) Collaborators
Aug 1, 2013·Physiological Reviews·Erik A Richter, Mark Hargreaves
Sep 2, 2014·Preventive Medicine·Claudia Ciceri CesaLucia Campos Pellanda
Oct 21, 2014·PloS One·Eivind AadlandGeir Kåre Resaland
Dec 3, 2014·Preventive Medicine·Mai ChinapawJohannes Brug
Jan 21, 2016·Physiological Genomics·Nienke M SchutteEco J C de Geus
Feb 26, 2016·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·D P CliffD R Lubans
Jun 4, 2016·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·E van EkrisM J M Chinapaw
Sep 8, 2017·BMJ Open Sport & Exercise Medicine·Stephen R Bird, John A Hawley
Sep 25, 2017·Scandinavian Journal of Medicine & Science in Sports·E AadlandG K Resaland

❮ Previous
Next ❯

Citations

Feb 11, 2020·Scandinavian Journal of Medicine & Science in Sports·Mark HamerEmmanuel Stamatakis
Nov 17, 2020·Complementary Therapies in Medicine·Gabriela Cristina Dos SantosJosianne Rodrigues-Krause

❮ Previous
Next ❯

Software Mentioned

SPSS
KineSoft

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.