Does co-transcriptional regulation of alternative splicing mediate plant stress responses?

Nucleic Acids Research
Ibtissam JabreNaeem H Syed

Abstract

Plants display exquisite control over gene expression to elicit appropriate responses under normal and stress conditions. Alternative splicing (AS) of pre-mRNAs, a process that generates two or more transcripts from multi-exon genes, adds another layer of regulation to fine-tune condition-specific gene expression in animals and plants. However, exactly how plants control splice isoform ratios and the timing of this regulation in response to environmental signals remains elusive. In mammals, recent evidence indicate that epigenetic and epitranscriptome changes, such as DNA methylation, chromatin modifications and RNA methylation, regulate RNA polymerase II processivity, co-transcriptional splicing, and stability and translation efficiency of splice isoforms. In plants, the role of epigenetic modifications in regulating transcription rate and mRNA abundance under stress is beginning to emerge. However, the mechanisms by which epigenetic and epitranscriptomic modifications regulate AS and translation efficiency require further research. Dynamic changes in the chromatin landscape in response to stress may provide a scaffold around which gene expression, AS and translation are orchestrated. Finally, we discuss CRISPR/Cas-based strat...Continue Reading

References

May 29, 1997·Nature·T MisteliD L Spector
Dec 5, 1998·Nucleic Acids Research·G C RobertsC W Smith
Oct 11, 2003·Molecular Cell·Manuel de la MataAlberto R Kornblihtt
Aug 16, 2005·The Plant Journal : for Cell and Molecular Biology·Koichi Hori, Yuichiro Watanabe
Jul 4, 2006·The Plant Journal : for Cell and Molecular Biology·Luis Arciga-ReyesBrendan Davies
Aug 22, 2006·Nature Structural & Molecular Biology·Imke ListermanKarla M Neugebauer
Dec 13, 2006·Nucleic Acids Research·Eddo KimGil Ast
Jan 17, 2007·Biochemistry. Biokhimii︠a︡·A M SchwartzJ G Atabekov
Feb 27, 2007·The Plant Journal : for Cell and Molecular Biology·Saiprasad Goud PalusaAnireddy S N Reddy
Jun 15, 2007·Plant & Cell Physiology·Koichi Hori, Yuichiro Watanabe
Apr 15, 2008·Nature·Travis N MavrichB Franklin Pugh
May 3, 2008·The EMBO Journal·Zoltán KerényiDániel Silhavy
Feb 26, 2009·Cell·Markus C WahlReinhard Lührmann
Jun 27, 2009·PLoS Genetics·Frank JohannesVincent Colot
Aug 5, 2009·Plant Molecular Biology·Tünde NyikóDániel Silhavy
Aug 18, 2009·Nature Structural & Molecular Biology·Hagen TilgnerRoderic Guigó
Aug 18, 2009·Nature Structural & Molecular Biology·Schraga SchwartzGil Ast
Oct 14, 2009·Cell Cycle·Satu NahkuriJohn S Mattick
Nov 17, 2009·Plant Molecular Biology·Steven PenfieldKaren J Halliday
Jan 26, 2010·Nucleic Acids Research·Wei ChenLirong Zhang
Feb 6, 2010·Science·Reini F LucoTom Misteli
Mar 20, 2010·Biochemical Society Transactions·Craig G SimpsonJohn W S Brown
Apr 7, 2010·Annual Review of Biochemistry·Stephanie MohrNorbert Perrimon
May 7, 2010·Nature·Yoseph BarashBrendan J Frey
Jun 1, 2010·Nature·Ramakrishna K ChodavarapuMatteo Pellegrini
Oct 20, 2010·Proceedings of the National Academy of Sciences of the United States of America·Xian DengXiaofeng Cao
Nov 26, 2010·Molecular Cell·Fernando Carrillo OesterreichKarla M Neugebauer
Nov 26, 2010·Molecular Cell·Ross D AlexanderJean D Beggs

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Citations

Apr 24, 2020·Critical Reviews in Biotechnology·Margaret ScarrowGenlou Sun
Jul 14, 2020·Wiley Interdisciplinary Reviews. RNA·Rebekah Eleazer, Yvonne N Fondufe-Mittendorf
Sep 2, 2020·Biochemical Society Transactions·Paola PunzoGiorgia Batelli
Jul 30, 2019·Frontiers in Plant Science·Tanushri KaulPawan Kumar Agrawal
Mar 7, 2020·Frontiers in Plant Science·Barbara Anna NimethMaria Kalyna
Jan 11, 2020·Frontiers in Plant Science·Luíza L B DantasCarlos T Hotta
Sep 26, 2020·Frontiers in Genetics·Jian ZhangCheng-Guo Duan
Jun 28, 2019·Frontiers in Plant Science·Saurabh ChaudharyNaeem H Syed
Jul 28, 2020·Plants·David Zalabák, Yoshihisa Ikeda
Nov 15, 2019·Nucleic Acids Research·Geoffray MonteuuisJohn E J Rasko
Oct 18, 2020·International Journal of Molecular Sciences·Jack ColicchioLena Hileman
Oct 25, 2020·Biological Reviews of the Cambridge Philosophical Society·Margaret ScarrowGenlou Sun
Nov 3, 2020·The New Phytologist·Ibtissam JabreNaeem H Syed
Jan 29, 2020·Molecular Plant·Yueying Zhang, Yiliang Ding
Mar 4, 2021·Journal of Integrative Plant Biology·Guoxiang JiangXuewu Duan
Jul 31, 2021·Plant Communications·Rocío Soledad Tognacca, Javier Francisco Botto

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Methods Mentioned

BETA
environmental stresses
environmental stress

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