Does Colchicine Substitute Corticosteroids in Treatment of Idiopathic and Viral Pediatric Pericarditis?

Vladislav VukomanovicGordana Petrović


Background and Objectives: Recurrence of pericarditis (ROP) is an important complication of the acute pericarditis. The aim of this study was to analyse the influence of aetiology, clinical findings and treatment on the outcome of acute pericarditis. Methods: Data were retrospectively collected from medical records of patients treated from 2011 to 2019 at a tertiary referent heart paediatric center. Results: Our investigation included 56 children with idiopathic and viral pericarditis. Relapse was registered in 8/56 patients, 2/29 (7.41%) treated with nonsteroidal anti-inflammatory drugs (NSAID) and 6/27 (28.57%) treated with corticosteroids (CS) and NSAID. Independent risk factors for ROP were viral pericarditis (p = 0.01, OR 31.46), lack of myocardial affection (p = 0.03, OR 29.15), CS use (p = 0.02, OR 29.02) and ESR ≥ 50 mm/h (p = 0.03, OR 25.23). In 4/8 patients the first recurrence was treated with NSAID and colchicine, while treatment of 4/8 patients included CS. Children with ROP treated with CS had higher median number of recurrence (5, IQR: 2-15) than those treated with colchicine (0, IQR: 0-0.75). Conclusions: Independent risk factors for recurrence are CS treatment, viral aetiology, pericarditis only and ESR ≥ 50 mm...Continue Reading


Aug 23, 2003·Journal of the American College of Cardiology·Marja RaatikkaEero V Jokinen
May 4, 2004·European Heart Journal·Bernhard MaischUNKNOWN Task Force on the Diagnosis and Management of Pricardial Diseases of the European Society of Cardiology
May 24, 2006·European Heart Journal·Pierre-Yves LevyDidier Raoult
Jun 28, 2006·Journal of Cardiovascular Medicine·Mauro Pepi, Manuela Muratori
Mar 6, 2009·Journal of Cardiovascular Medicine·Massimo ImazioYehuda Adler
Aug 14, 2009·Expert Review of Cardiovascular Therapy·Massimo ImazioYehuda Adler
Jul 16, 2010·The American Journal of Emergency Medicine·David M DrossnerHarold K Simon
Dec 21, 2010·Clinical Reviews in Allergy & Immunology·Luca CantariniMauro Galeazzi
May 3, 2011·Current Infectious Disease Reports·Massimo Imazio
Jun 30, 2011·Pediatric Emergency Care·Savithiri RatnapalanLee Benson
Feb 1, 2012·Current Problems in Cardiology·David M DudzinskiJudy W Hung
Jul 5, 2013·European Heart Journal·Alida L P CaforioUNKNOWN European Society of Cardiology Working Group on Myocardial and Pericardial Diseases
Sep 3, 2013·The New England Journal of Medicine·Massimo ImazioUNKNOWN ICAP Investigators
Nov 9, 2014·Journal of the American Heart Association·Divya ShaktiJane W Newburger
Oct 16, 2015·JAMA : the Journal of the American Medical Association·Massimo ImazioMartin LeWinter
Apr 17, 2016·Archives of Disease in Childhood·Samer AlabedAmanda Burls
Jul 29, 2016·Journal of Cardiovascular Medicine·Massimo ImazioAlberto Martini
Nov 26, 2016·Journal of the American College of Cardiology·Paul C CremerAllan L Klein
Jun 3, 2017·Journal of the American College of Cardiology·Antonio BrucatoBernhard Maisch

❮ Previous
Next ❯

Methods Mentioned


Software Mentioned


Related Concepts

Related Feeds


Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

Related Papers

Cleveland Clinic Journal of Medicine
Heath Saltzman, Howard H Weitz
European Heart Journal
Antoni Bayes-GenisMassimo Imazio
C EscobarM Seguí Díaz
American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists
Lovely Chhabra, David H Spodick
Duodecim; lääketieteellinen aikakauskirja
Jukka Lehtonen
© 2021 Meta ULC. All rights reserved