Does diabetes mellitus change the carpal tunnel release outcomes? Evidence from a systematic review and meta-analysis.

Journal of Hand Therapy : Official Journal of the American Society of Hand Therapists
Ali MoradiHassan Mehrad-Majd

Abstract

A systematic review and meta-analysis. Carpal tunnel syndrome (CTS) is one of the most common upper extremity conditions which mostly affect women. Management of patients suffering from both CTS and diabetes mellitus (DM) is challenging, and it was suggested that DM might affect the diagnosis as well as the outcome of surgical treatment. This meta-analysis was aimed to compare the response with CTS surgical treatment in diabetic and nondiabetic patients. Electronic databases were searched to identify eligible studies comparing the symptomatic, functional, and neurophysiological outcomes between diabetic and nondiabetic patients with CTS. Pooled MDs with 95% CIs were applied to assess the level of outcome improvements. Ten articles with 2869 subjects were included. The sensory conduction velocities in the wrist-palm and wrist-middle finger segments showed a significantly better improvement in nondiabetic compared with diabetic patients (MD = -4.31, 95% CI = -5.89 to -2.74, P < .001 and MD = -2.74, 95% CI = -5.32 to -0.16, P = .037, respectively). However, no significant differences were found for the improvement of symptoms severity and functional status based on the Boston Carpal Tunnel Questionnaire and Quick Disabilities of t...Continue Reading

Citations

Mar 7, 2021·International Journal of Environmental Research and Public Health·Mar Hernández-SecorúnMaría Orosia Lucha-López
May 22, 2021·Journal of Hand Therapy : Official Journal of the American Society of Hand Therapists·Shravya A JoshiKarthik Hariharan
Jul 4, 2021·Diabetes Research and Clinical Practice·Georgia SamakidouNikolaos Tentolouris
Jul 16, 2021·Journal of the Chinese Medical Association : JCMA·Chen-Wen HuangJung-Pan Wang

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