DOI: 10.1101/19007005Oct 8, 2019Paper

Does e-cigarette use in non-smoking young adults act as a gateway to smoking? A systematic review and meta-analysis

MedRxiv : the Preprint Server for Health Sciences
Jasmine N KhoujaMarcus R Munafò

Abstract

Objective: The aim of this review was to investigate whether e-cigarette use compared to non-use in young non-smokers is associated with subsequent cigarette smoking. Data sources: PubMed, Embase, Web of Science, Wiley Cochrane Library databases, and the 2018 Society for Research on Nicotine and Tobacco and Society for Behavioural Medicine conference abstracts. Study selection: All studies of young people (up to age 30 years) with a measure of e-cigarette use prior to smoking and an outcome measure of smoking where an odds ratio could be calculated were included (excluding reviews and animal studies). Data Extraction: Independent extraction was completed by multiple authors using a pre-prepared extraction form. Data synthesis: Of 9,199 results, 17 studies were included in the meta-analysis. There was strong evidence for an association between e-cigarette use among non-smokers and later smoking (OR 4.59, 95% CI 3.60 to 5.85) when the results were meta-analysed in a random effects model. However, there was high heterogeneity (I2 = 88%). Conclusions: Whilst the association between e-cigarette use among non-smokers and subsequent smoking appears strong, the available evidence is limited by the reliance on self-report measures of sm...Continue Reading

Citations

Aug 27, 2021·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Benjamin R Chand, Hassan Hosseinzadeh

❮ Previous
Next ❯

Software Mentioned

Google translate
Review Manager
Stata SE
Covidence

Related Concepts

Related Feeds

BioRxiv & MedRxiv Preprints

BioRxiv and MedRxiv are the preprint servers for biology and health sciences respectively, operated by Cold Spring Harbor Laboratory. Here are the latest preprint articles (which are not peer-reviewed) from BioRxiv and MedRxiv.