PMID: 16532226Mar 15, 2006Paper

Does endothelial dysfunction correlate better with waist-to-hip ratio than with body mass index or waist circumference among obese patients?

Clinics
Nivaldo Ribeiro VillelaEliete Bouskela

Abstract

Obesity is associated with cardiovascular disease, affecting large arteries and the microcirculation. Waist circumference and body mass index are routinely employed as measures for assessing obesity-related health risk, whereas waist-to-hip ratio is not. We aimed to investigate the association between brachial vascular reactivity and body mass index, waist circumference, and waist-to-hip ratio. Eighty-five volunteers (21 men/66 women), aged between 20 and 55 years, underwent determination of waist circumference, body mass index, waist-to-hip ratio, and endothelial function by venous occlusion plethysmography. Forearm blood flow was measured in response to intrabrachial artery infusions of 3 different concentrations of endothelium-dependent (acetylcholine 7.5, 15, and 30 mg/min) and endothelium-independent (sodium nitroprusside 2, 4, and 8 mg/min) vasodilators. There was an inverse correlation of body mass index and waist circumference with forearm blood flow increments after acetylcholine and sodium nitroprusside infusions, while waist-to-hip ratio showed an inverse correlation with forearm blood flow increments only after acetylcholine. When subjects older than 40 years (n = 25) were excluded from the analysis, the inverse cor...Continue Reading

Citations

Aug 13, 2013·American Journal of Physiology. Heart and Circulatory Physiology·Jacqueline K LimbergWilliam G Schrage
May 26, 2009·Arquivos brasileiros de endocrinologia e metabologia·Nivaldo Ribeiro VillelaEliete Bouskela
Dec 11, 2007·Anais Da Academia Brasileira De Ciências·Nicolas WiernspergerEliete Bouskela
Apr 8, 2014·Physiological Research·I AbdoC Lehmann
Jun 18, 2010·Regulatory Peptides·Maren SkauRigmor Jensen

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Anxiety Disorders

Discover the latest research on anxiety disorders including agoraphobia, panic disorder, obsessive-compulsive disorder, and post-traumatic stress disorder here.

Related Papers

Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition
Chu-Chih ChenYi-Ju Chen
Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
James O BurtonNigel J Brunskill
© 2021 Meta ULC. All rights reserved