Does etiology of acute pancreatitis matter? A review of 391 consecutive episodes

JOP : Journal of the Pancreas
Gunther WeitzKlaus Fellermann

Abstract

Acute pancreatitis can be triggered by a variety of factors ranging from short lasting to sustained disruptions. It is plausible that the characteristics and course of disease differ among etiologies. Data distinguishing characteristics of patients with pancreatitis of biliary, alcoholic, idiopathic or other origin are scarce and conflicting. To compare patients' characteristics, baseline parameters on admission, and outcome in patients with an episode of acute pancreatitis in whom the etiology was thoroughly determined. Retrospective study. Single center. Three-hundreds and 91 consecutive episodes of acute pancreatitis through the years 2008 to 2011. Gender, age, body mass index, Charlson comorbidity index, history of pancreatitis, heart rate, blood pressure, plasma lipase, hematocrit, plasma creatinine, white blood cell count, rate of persistent organ failure and necrosis, maximum C-reactive protein, duration of hospitalization, mortality. There were marked differences between the groups. Biliary etiology was associated with higher age and body weight, female predominance, higher plasma lipase, and a favourable outcome. Alcoholic etiology had male predominance, a tendency for initial hemoconcentration, a lower plasma lipase, ...Continue Reading

Citations

Feb 2, 2021·Frontiers in Surgery·Jonas HennHanno Matthaei
Apr 4, 2021·Journal of Clinical Medicine·Mathias SchmandtStefan Felix Ehrentraut

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