Does Family History of Obesity, Cardiovascular, and Metabolic Diseases Influence Onset and Severity of Childhood Obesity?

Frontiers in Endocrinology
Domenico CoricaMalgorzata Wasniewska

Abstract

The objectives were to evaluate (1) the metabolic profile and cardiometabolic risk in overweight/obese children at first assessment, stratifying patients according to severity of overweight and age; and (2) to investigate the relationship between family history (FH) for obesity and cardiometabolic diseases and severity of childhood obesity. In this cross-sectional, retrospective, observational study, 260 children (139 female), aged between 2.4 and 17.2 years, with overweight and obesity were recruited. Data regarding FH for obesity and cardiometabolic diseases were collected. Each patient underwent clinical and auxological examination and fasting blood sampling for metabolic profile. Homeostasis model assessment of insulin resistance (HOMA-IR), triglyceride-to-high-density lipoprotein cholesterol ratio, and atherogenic index of plasma were calculated. To evaluate the severity of obesity, children were divided into two groups for BMI standard deviation (SD) ≤2.5 and BMI SD >2.5. Moreover, study population was analyzed, dividing it into three groups based on the chronological age of patient (<8, 8-11, >11 years). BMI SD was negatively correlated with chronological age (p < 0.005) and significantly higher in the group of children ...Continue Reading

References

Sep 26, 1997·The New England Journal of Medicine·R C WhitakerW H Dietz
Jan 9, 2004·Epidemiology·Anders EngelandAnne Johanne Søgaard
Jun 4, 2004·The New England Journal of Medicine·Ram WeissSonia Caprio
May 24, 2005·BMJ : British Medical Journal·John J ReillyUNKNOWN Avon Longitudinal Study of Parents and Children Study Team
Sep 15, 2007·Archives of Disease in Childhood·Nikki J BlairEdwin A Mitchell
Nov 21, 2007·Bulletin of the World Health Organization·Mercedes de OnisJonathan Siekmann
Feb 15, 2008·Diabetes Care·Ram Weiss, Francine Ratner Kaufman
Mar 12, 2008·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·A S SinghM J M Chinapaw
Sep 16, 2009·Pediatrics·David S Freedman, Bettylou Sherry
Feb 12, 2010·The New England Journal of Medicine·Paul W FranksHelen C Looker
Aug 11, 2011·Archives of Disease in Childhood·Mary Rudolf
Nov 18, 2011·The New England Journal of Medicine·Markus JuonalaOlli T Raitakari
Jun 27, 2012·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·M H ParkS Kinra
Oct 24, 2012·European Journal of Pediatrics·Rade VukovicDragan Zdravkovic
Oct 30, 2013·European Journal of Endocrinology·Tommaso de GiorgisAngelika Mohn
Jan 1, 2014·Journal of Clinical Research in Pediatric Endocrinology·Yashpal SinghRaman Kumar Marwaha
Nov 8, 2014·International Journal of Obesity : Journal of the International Association for the Study of Obesity·W AhrensUNKNOWN IDEFICS consortium
Oct 1, 2015·The New England Journal of Medicine·Asheley C SkinnerJoseph A Skelton

❮ Previous
Next ❯

Citations

May 28, 2019·Journal of Pediatric Endocrinology & Metabolism : JPEM·Anoop Mohamed IqbalSeema Kumar
Mar 21, 2020·Frontiers in Endocrinology·Domenico CoricaMalgorzata Wasniewska
Feb 12, 2021·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Fernanda Barrinha FernandesDulce Elena Casarini
Mar 5, 2021·Cytokine·Domenico CoricaMalgorzata Wasniewska
Jun 23, 2021·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Yoichi Nozato, Koichi Yamamoto
Oct 1, 2020·Saudi Journal of Biological Sciences·May Salem Al-Nbaheen

❮ Previous
Next ❯

Software Mentioned

SPSS

Related Concepts

Related Feeds

CV Disorders & Type 2 Diabetes

This feed focuses on the association of cardiovascular diseases in patients with type 2 diabetes.