Does first line antiretroviral therapy increase the prevalence of cardiovascular risk factors in Indian patients?: A cross sectional study

Journal of Postgraduate Medicine
R A B CareyD Kattula

Abstract

Antiretroviral therapy (ART) is associated with a myriad of metabolic complications which are potential cardiovascular risk factors. Early detection of these risk factors could help in alleviating morbidity and mortality in human immunodeficiency virus (HIV) infected patients on ART. To study the prevalence of cardiovascular risk factors in patients on a combination of nucleoside reverse transcriptase inhibitors (NRTIs) and non-NRTIs (NNRTIs) - the standard combination first line ART regimen used in tertiary referral center. The prevalence of cardiovascular risk factors in HIV infected subjects with stage 1t disease on standard first line ART for at least 1 year, HIV infected subjects with stage 1 disease and not on ART and HIV negative subjects was assessed. The study was a cross-sectional study design. Basic demographic data was collected and patients were examined for anthropometric data and blood was collected for analysis of blood glucose, serum lipids, and fasting insulin levels. Chi-square test was used to calculate significance. Statistical Package for Social Sciences (SPSS) software version 16.0 was used for data analysis. The prevalence of hypercholesterolemia and hypertriglyceridemia was higher in the patients on ART...Continue Reading

References

Apr 11, 1996·The New England Journal of Medicine·J P DesprésP J Lupien
Aug 26, 1998·The Journal of Clinical Endocrinology and Metabolism·R S LegroA Dunaif
Oct 29, 2000·Lancet·A Carr, D A Cooper
Feb 21, 2003·The New England Journal of Medicine·Daniel R Kuritzkes, Judith Currier
Dec 29, 2006·Diabetes Care·UNKNOWN American Diabetes Association
May 4, 2007·Journal of Cardiopulmonary Rehabilitation and Prevention·Yong-Ho Lee, Richard E Pratley
Jan 14, 2011·European Heart Journal·Jason V Baker, Jens D Lundgren
Apr 22, 2011·Journal of the International Association of Physicians in AIDS Care : JIAPAC·Annie Phoebe KalyanasundaramMampakkam Rajappa Sivakumar
Sep 29, 2011·AIDS Research and Therapy·Eric Walter Pefura YoneJeanne Ngogang

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