Does implantation of larger bioprosthetic pulmonary valves in young patients guarantee durability in adults? Durability analysis of stented bioprosthetic valves in the pulmonary position in patients with Tetralogy of Fallot †

European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery
Jae Gun KwakSeong-Ho Kim

Abstract

In a previous study, we identified factors affecting the durability of bioprosthetic valves in the pulmonary position following total repair of Tetralogy of Fallot (TOF). In this study, we aimed to identify factors affecting the durability of the bioprosthetic valve with regard to patient age and implanted valve size in order to guide valve choice in adolescent patients. We enrolled and analysed 108 cases of pulmonary valve replacement (PVR) with stented bioprosthetic valves in TOF patients between January 1998 and February 2014. Valvular dysfunction was defined as at least a moderate amount of pulmonary regurgitation or a peak pressure gradient of ≥40 mmHg on the most recent echocardiography. We analysed the effect of patient age and valve size on the durability of the bioprosthetic valve in the pulmonary position. There were 2 early deaths; no late deaths were observed. The follow-up duration was 92.8 ± 44.5 months. The mean age at PVR was 19.3 ± 9.1 years. The mean valve size was 24.7 ± 1.8 mm. Whereas patients ≥20 years old showed no valvular dysfunction (i.e. 100% freedom from valvular dysfunction at 10 and 14 years), patients who were adolescents and children (<20 years) showed worse durability, regardless of the z-score ...Continue Reading

References

Oct 1, 1981·The Annals of Thoracic Surgery·J M Dunn
Nov 1, 1996·The Annals of Thoracic Surgery·J I FannN E Shumway
Nov 23, 2000·The Journal of Thoracic and Cardiovascular Surgery·C A CaldaroneW G Williams
Feb 15, 2001·The Journal of Thoracic and Cardiovascular Surgery·B DiscigilG K Danielson
Jul 21, 2004·Journal of the American College of Cardiology·Guangqiang GaoAlbert Starr
Dec 2, 2004·Expert Opinion on Biological Therapy·Dan T Simionescu
May 16, 2009·Journal of the American College of Cardiology·Tarek S MomenahPhilipp Bonhoeffer
Jan 21, 2012·The Korean Journal of Thoracic and Cardiovascular Surgery·Hye-Won KimTae-Jin Yoon
Jul 5, 2012·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Cheul LeeYang Min Kim
Jan 22, 2013·Cardiology in the Young·Cheul LeeJames A Quintessenza
Apr 1, 2010·World Journal for Pediatric & Congenital Heart Surgery·James Anthony QuintessenzaHarald Lindberg
Jan 10, 2014·Cardiology in the Young·Cheul LeeJae Gun Kwak
Feb 11, 2014·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Dai UneTirone E David

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Citations

Sep 14, 2018·General Thoracic and Cardiovascular Surgery·Maziar Gholampour DehakiMahyar Gholampour Dehaki
Aug 17, 2019·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Aimee K ArmstrongDoff B McElhinney
Feb 23, 2020·Frontiers in Bioengineering and Biotechnology·Guangyu ZhuJoon Hock Yeo
Sep 29, 2020·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Shuhei FujitaHitoshi Yaku
Apr 17, 2018·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Douglas BellNelson Alphonso
Feb 6, 2018·The Journal of Thoracic and Cardiovascular Surgery·Allison K CabalkaDoff B McElhinney
May 11, 2021·Seminars in Thoracic and Cardiovascular Surgery·Katsuhide MaedaDoff B McElhinney
Feb 6, 2020·The Journal of Thoracic and Cardiovascular Surgery·Jae Gun KwakWoong-Han Kim

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