Does measuring respiratory function improve neonatal ventilation?

Journal of Paediatrics and Child Health
Jan KlimekPeter G Davis

Abstract

To determine whether using a respiratory function monitor alters clinicians' choice of ventilator settings, tidal volumes or blood gases in the first 48 h of ventilation. Clinicians were trained to use a respiratory function monitor to optimize neonatal ventilation. Thirty-five infants, weighing < 2 kg, treated with the Infant Star ventilator were randomized to have a respiratory function monitor display visible or concealed. All reasons for altering ventilator settings were noted. Data on ventilator parameters and clinical care were collected hourly. The primary outcome was the mean peak pressure used during the first 48 h. There were no statistically significant differences in peak pressures, tidal volumes or arterial carbon dioxide levels between the two groups. Using the Florian respiratory function monitor in the first 48 h of ventilation with the Infant Star ventilator did not alter the choice of ventilator settings, tidal or minute volumes or arterial blood gases. Possible explanations for this result include lack of power due to the small numbers recruited and bias due to the unblinded nature of the trial.

References

Aug 1, 1993·The American Review of Respiratory Disease·G BernsteinF L Mannino
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Citations

Nov 10, 2011·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Vincent RigoJacques Rigo
Jul 21, 2014·The Journal of Pediatrics·Jeroen J van VonderenArjan B te Pas
Nov 8, 2011·The Journal of Pediatrics·Georg M SchmölzerPeter G Davis
Oct 4, 2014·PloS One·Jeroen J van VonderenArjan B te Pas
Sep 9, 2010·The Cochrane Database of Systematic Reviews·Georg M SchmölzerPeter G Davis
Jun 29, 2010·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Ramadan A MahmoudGerd Schmalisch
Sep 20, 2019·Acta Paediatrica·Arrabella KingAtul Malhotra

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