Does microalbuminuria predict illness severity in critically ill patients on the intensive care unit? A systematic review

Critical Care Medicine
Shameer GopalPaul Nelson

Abstract

Studies assessing the accuracy of microalbuminuria to predict illness severity on the intensive care unit have produced inconsistent results. To determine the diagnostic accuracy of microalbuminuria to predict illness severity in critically ill patients on the intensive care unit. MEDLINE (1951 to September 2004) and EMBASE (1980 to September 2004) electronic databases were searched for relevant studies. Reference lists of all abstracts were manually searched to identify studies not included in the electronic database. Studies that prospectively evaluated the accuracy of microalbuminuria to predict illness severity and/or mortality probability in adult patients on the intensive care unit were selected. We included nine studies in the review. Data to evaluate methodological quality and results were abstracted. The methodological quality of a number of studies was poor. Significant heterogeneity in the design and conduct of the studies circumvented the data being subjected to meta-analysis. Studies also differed in the timing of the index test, in the methods of quantifying microalbuminuria, and in the cutoff values used. This descriptive analysis reveals that microalbuminuria may hold promise as a predictor of illness severity a...Continue Reading

References

Oct 26, 1978·The New England Journal of Medicine·D F Ransohoff, A R Feinstein
Apr 1, 1991·European Heart Journal·P GoslingJ P Fox
Nov 1, 1989·Journal of Clinical Pathology·C P ShearmanK J Walker
Jun 4, 1988·British Medical Journal·P GoslingA J Sutcliffe
Oct 1, 1985·Critical Care Medicine·W A KnausJ E Zimmerman
Nov 1, 1984·Critical Care Medicine·J R Le GallD Villers
Oct 1, 1995·Critical Care Medicine·J C MarshallW J Sibbald
Jan 1, 1995·Journal of Clinical Epidemiology·L IrwigM Fahey
Dec 22, 1993·JAMA : the Journal of the American Medical Association·J R Le GallF Saulnier
Aug 14, 1999·Arteriosclerosis, Thrombosis, and Vascular Biology·K Borch-JohnsenJ S Jensen
Sep 24, 1999·JAMA : the Journal of the American Medical Association·J G LijmerP M Bossuyt
Apr 1, 2000·British Journal of Anaesthesia·K L MacKinnonE Shearer
Jul 31, 2001·JAMA : the Journal of the American Medical Association·H C GersteinUNKNOWN HOPE Study Investigators
Jul 5, 2002·BMC Medical Research Methodology·Walter L DevilléP Dick Bezemer
Jan 1, 2003·Clinical Chemistry·Patrick M BossuytUNKNOWN Standards for Reporting of Diagnostic Accuracy
Feb 1, 2003·Intensive Care Medicine·Zsolt MolnárPéter Heigl
Apr 12, 2003·Critical Care Medicine·Natalya ThorevskaYaw Amoateng-Adjepong
May 23, 2003·Intensive Care Medicine·Peter GoslingJohn Czyz
Jun 26, 2003·Journal of Internal Medicine·C E Mogensen
Nov 9, 2004·Journal of Diabetes and Its Complications·Hillary A TuttlePaul F McDonagh

❮ Previous
Next ❯

Citations

Apr 1, 2010·Indian Journal of Clinical Biochemistry : IJCB·Surupa BasuA Majumdar
May 23, 2006·Critical Care Medicine·Peter Gosling
Apr 11, 2008·Critical Care Medicine·Sean M Bagshaw, R T Noel Gibney
Jul 8, 2010·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Surupa BasuArghya Majumdar
Feb 2, 2008·Wiener klinische Wochenschrift·Wilfred Druml, Michael Hiesmayr
Jul 5, 2008·Expert Review of Molecular Diagnostics·Robert Keyes, Sean M Bagshaw
Jun 15, 2012·Scandinavian Cardiovascular Journal : SCJ·Chiara LazzeriGian Franco Gensini
Jan 22, 2010·International Journal of Stroke : Official Journal of the International Stroke Society·A RoccoTh Steiner
Oct 20, 2010·Journal of Veterinary Emergency and Critical Care·Shelly L VadenSteven L Marks
May 19, 2010·Journal of Cardiovascular Medicine·Chiara LazzeriGian F Gensini
Nov 3, 2007·Current Opinion in Critical Care·Sean M Bagshaw, Rinaldo Bellomo
Jul 4, 2008·JPEN. Journal of Parenteral and Enteral Nutrition·Gil Hardy, Ines J Hardy
Jun 4, 2014·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Ayse Berna AnilMehmet Helvaci
Mar 6, 2021·Australian Critical Care : Official Journal of the Confederation of Australian Critical Care Nurses·L WeinelL Chapple
Aug 31, 2020·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Anil SachdevParul Chugh
May 7, 2021·Critical Care Research and Practice·Mahmoud NourMohamed Fawzy
Sep 12, 2021·Diabetes Research and Clinical Practice·Jianrong YangWensheng Lu

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.