Abstract
Blood stasis is the main cause of left atrial thrombosis (LAT) in atrial tachyarrhythmias. The high-velocity flow inside the left atrium, due to mitral valve regurgitation, may prevent clot formation but the topic has never been investigated in large-scale studies. The aim of our study was to evaluate whether the presence and degree of mitral regurgitation have a protective role against LAT risk. A total of 1302 consecutive adult patients with paroxysmal or persistent atrial fibrillation or flutter undergoing cardioversion, submitted to transesophageal echocardiography, were retrospectively enrolled in the study. The study population was divided into three groups according to the mitral regurgitation degree: absent, mild-to-moderate and severe. Among 1302 patients enrolled in the study, patients without mitral regurgitation were 248 (19%), those with mild-to-moderate 970 (75%), whereas 84 had severe mitral regurgitation (6%). LAT incidence was significantly lower in patients with severe mitral regurgitation compared with those with mild-to-moderate (mitral regurgitation) (2.4 vs. 8.9%, P < 0.05), and similar to subjects without mitral regurgitation (2.4%). Despite patients with severe regurgitation having clinical and echo char...Continue Reading
References
Aug 1, 1995·The American Journal of Cardiology·G T KaratasakisD V Cokkinos
Mar 1, 1994·Journal of the American College of Cardiology·A MüggeW G Daniel
Mar 1, 1993·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·C MovsowitzM N Kotler
May 1, 1997·Heart·R M HeppellJ A Davies
Dec 31, 1997·Journal of the American College of Cardiology·H F TseG Cheng
Nov 17, 1998·The American Journal of Cardiology·M OzkanU Deligonul
Dec 10, 1999·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·M E GoldmanJ L Halperin
Mar 15, 2000·International Journal of Cardiology·Y MiyasakaT Iwasaka
Jan 5, 2001·Pacing and Clinical Electrophysiology : PACE·A KranidisN Exadaktylos
May 11, 2001·The New England Journal of Medicine·A L KleinUNKNOWN Assessment of Cardioversion Using Transesophageal Echocardiography Investigators
Nov 28, 2002·Japanese Heart Journal·Nihal OzdemirMehmet Ozkan
Oct 19, 2004·Echocardiography·Angel López-Candales, Kathy L Edelman
Nov 15, 2005·Heart·A MaltagliatiM Pepi
Aug 19, 2008·International Journal of Cardiology·Kensuke KimuraKeiichi Fukuda
Aug 12, 2009·International Journal of Cardiology·Nobuyuki FukudaHiroshi Inoue
Sep 19, 2009·Chest·Gregory Y H LipHarry J G M Crijns
Oct 9, 2009·Clinical Cardiology·Chandra K NairDennis J Esterbrooks
Nov 6, 2009·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Bogdan A PopescuJos R T C Roelandt
Aug 13, 2010·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Mauro PepiUNKNOWN European Association of Echocardiography
Mar 29, 2011·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Srilatha AyiralaDavid I Silverman
Aug 10, 2011·Journal of cardiology·Shota FukudaJunichi Yoshikawa
Jun 5, 2013·European Heart Journal Cardiovascular Imaging·Patrizio LancellottiUNKNOWN Scientific Document Committee of the European Association of Cardiovascular Imaging
Feb 26, 2015·European Heart Journal Cardiovascular Imaging·Roberto M LangJens-Uwe Voigt
May 29, 2015·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Alberto CrestiSilva Severi
Feb 13, 2016·European Heart Journal Cardiovascular Imaging·Erwan DonalAriel Cohen
Aug 28, 2016·European Heart Journal·Paulus KirchhofUNKNOWN ESC Scientific Document Group
Jun 1, 2016·JACC. Clinical Electrophysiology·Daniel FrenkelJim W Cheung