Does Multimodal Rehabilitation for Ankle Instability Improve Patients' Self-assessed Functional Outcomes? A Network Meta-analysis

Clinical Orthopaedics and Related Research
Konstantinos TsikopoulosHaris S Vasiliadis

Abstract

Although there are many nonsurgical treatment options for the primary management of chronic ankle instability, the most effective nonoperative intervention has not been defined. The purpose of this study was to perform a network meta-analysis to compare the results of different standalone and/or combined nonsurgical interventions on chronic ankle instability as measured by (1) the Cumberland Ankle Instability Tool (CAIT) at 0 to 6 months after treatment and (2) treatment-related complications. We searched PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), and Scopus in August 2017 for completed studies published between 2005 and 2016. We conducted random-effects pairwise and network meta-analysis considering randomized trials, which compared the effects of various nonoperative therapies for ankle instability. Studies assessing patients with functional ankle instability and/or mechanical ankle instability and/or recurrent ankle sprains were eligible for inclusion. After combining data from self-administered questionnaires, we analyzed patient self-reported outcomes of function at the end of the rehabilitation period and 1 to 6 months after treatment. We thereafter reexpressed standardized mean differences to mean ...Continue Reading

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Citations

Oct 19, 2019·Clinical Orthopaedics and Related Research·Konstantinos TsikopoulosAshique Ali
Oct 21, 2020·The American Journal of Sports Medicine·Brandon J ManderleNikhil N Verma
Oct 6, 2020·Journal of Sport and Health Science·Xiao'ao XueYinghui Hua
Apr 2, 2021·The Journal of Orthopaedic and Sports Physical Therapy·Robroy L MartinDominic Carreira

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