Does normal ageing alter right ventricular relaxation properties? A tissue Doppler study

Heart, Lung & Circulation
Joseph ChihaLiza Thomas

Abstract

Even in 'healthy' individuals, ageing alters left ventricular diastolic function with a decrease in early diastolic filling. There is a paucity of data with regards to right ventricular (RV) parameters with normal ageing. We sought to determine the effect of ageing on RV size and function in a group of 'healthy' individuals. We retrospectively analysed echocardiograms from 60 healthy volunteers in three age groups (20-80 years) from a departmental database. RV area and volume were measured from the apical 4-chamber view and indexed to body surface area. Pulsed-wave tissue Doppler Imaging (TDI) was used to obtain right ventricular lateral annular systolic and diastolic velocities. Using Colour Doppler Tissue Imaging (CDTI), mean peak segmental velocities in systole (S') and in diastole (E', and A') were measured from the annular and mid-segments of the lateral RV. There was no change observed in RV area, volume or ejection fraction with increasing age. RV systolic function evaluated by RVEF and S' velocity were also unchanged with ageing. There was a significant decrease in CDTI and pulsed-wave TDI E' velocity with age (p<0.05) with a corresponding increase in A' velocity. Normal ageing leads to impaired RV relaxation with a red...Continue Reading

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Citations

Sep 6, 2014·European Journal of Anaesthesiology·Jeroen WinkPatrick F Wouters
Sep 15, 2012·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Umberto D'OronzioMatthias Greutmann
Aug 16, 2016·Archives of Gerontology and Geriatrics·Roman LaszloJuergen Michael Steinacker
Sep 28, 2020·The International Journal of Cardiovascular Imaging·Nadjia KachenouraElie Mousseaux
Jan 22, 2020·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Samantha NelFerande Peters
Oct 26, 2021·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Cristiane Carvalho SingulaneRoberto M Lang

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