Does occupational exposure to PAHs, diesel and aromatic amines interact with smoking and metabolic genetic polymorphisms to increase the risk on bladder cancer?; The Belgian case control study on bladder cancer risk

Cancer Letters
Eliane KellenFrank Buntinx

Abstract

To investigate the association between occupational exposure to polycyclic aromatic hydrocarbons, aromatic amines and diesel and bladder cancer risk and the modification by smoking and metabolic polymorphisms, have we recruited 200 cases and 385 population controls. The adjusted OR of bladder cancer was 5.75 (95%CI 2.09-15.83) comparing the highest tertile of the cumulative probability of occupational exposure to aromatic amines with no occupational exposure. A possible interaction between occupational exposures to aromatic amines and smoking was found. The increased ORs of GSTM1, GSTT1, NAT2 and SULT1A1 among those ever occupational exposed was explored by estimating the false-positive report probability. We confirm that occupational exposure to aromatic amines is associated with an increase in bladder cancer risk.

References

Jun 25, 1990·Nucleic Acids Research·K E ComstockW D Henner
Oct 15, 1989·International Journal of Cancer. Journal International Du Cancer·S BonassiR Puntoni
Jun 1, 1993·International Journal of Epidemiology·S CordierD Hemon
Nov 14, 1997·Science·F P Perera
Apr 16, 1998·Occupational and Environmental Medicine·M KogevinasS Hoar-Zahm
Jan 4, 2001·Epidemiology·P Boffetta, D T Silverman
Jun 1, 2001·American Journal of Epidemiology·L D Botto, M J Khoury
Aug 21, 2001·Occupational and Environmental Medicine·M P ZeegersP A van den Brandt
Sep 6, 2001·Mutation Research·R C StrangeA A Fryer
Oct 23, 2003·Nature Reviews. Cancer·Stephen S Hecht
Nov 18, 2003·International Journal of Cancer. Journal International Du Cancer·Paolo VineisSeymour Garte
Jan 31, 2004·Cancer Causes & Control : CCC·Manolis KogevinasPaolo Boffetta
May 4, 2004·International Journal of Cancer. Journal International Du Cancer·Rayjean J HungStefano Porru
Jun 16, 2004·International Journal of Cancer. Journal International Du Cancer·Johannes GuoEero Pukkala
Nov 18, 2004·Journal of the National Cancer Institute·Hans-Hermann Dubben
Dec 31, 2004·American Journal of Human Genetics·Hua TangNeil J Risch
Jan 22, 2005·Nature Reviews. Cancer·Andreas Luch
Mar 8, 2005·Cancer Causes & Control : CCC·Nancy Krieger
Mar 12, 2005·CA: a Cancer Journal for Clinicians·D Max ParkinPaola Pisani
Apr 21, 2005·Journal of the National Cancer Institute·Giuseppe MatulloPaolo Vineis

❮ Previous
Next ❯

Citations

Oct 19, 2006·World Journal of Urology·Dragan J GolijaninSeth P Lerner
Jul 11, 2007·Journal of Cancer Research and Clinical Oncology·Yuan-Hung WangHung-Yi Chiou
Sep 26, 2009·Clinical and Experimental Medicine·Fang-Fang ZengBin-You Wang
Jan 1, 2010·Cancer Causes & Control : CCC·Maree T BrinkmanMaurice P Zeegers
Oct 25, 2011·American Journal of Public Health·Paul A SchulteHeeKyoung Chun
Nov 4, 2008·Clinical and Experimental Medicine·João Paulo Souto GrandoIlce Mara de Syllos Cólus
Sep 10, 2013·Drug Metabolism Reviews·Jaclyn Daniels, Susan Kadlubar
Dec 10, 2013·Journal of the Chinese Medical Association : JCMA·Zhon-Min HuangGuang-Dar Juang
May 26, 2011·Toxicology Letters·Glenn TalaskaRoel Vermeulen
Dec 15, 2015·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Wei-Chun WengYing-Erh Chou
Jan 6, 2009·International Journal of Urology : Official Journal of the Japanese Urological Association·Yuan-Hung WangHung-Yi Chiou
Sep 16, 2008·International Journal of Cancer. Journal International Du Cancer·Marjolein HemeltMaurice P A Zeegers
Jun 29, 2010·American Journal of Industrial Medicine·Anne PetersenBo Netterstrøm
Jun 21, 2016·Regulatory Toxicology and Pharmacology : RTP·Peter N LeeJanette S Hamling
May 12, 2011·Experimental Biology and Medicine·Zheng JiangXishan Wang
Apr 14, 2017·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·Jovana StojanovicStefania Boccia
Feb 6, 2008·Environmental Toxicology·Sung-Hwa SohnMeyoung-Kon Kim
Feb 29, 2008·American Journal of Industrial Medicine·Dongmug KangDavid Kriebel
Jun 19, 2008·Reviews on Environmental Health·Richard W ClappEdward L Loechler
Jun 28, 2013·Asian Pacific Journal of Cancer Prevention : APJCP·Loulou Hassan KobeissiHassan Rida Dhaini
Sep 10, 2014·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Wencheng Li, Min Gu
Feb 9, 2017·Nature Reviews. Urology·Alexander P GlaserJoshua J Meeks
Jun 23, 2010·Molecular Biology Reports·Lucia KlimčákováJozef Židzik
Oct 28, 2019·BMC Cancer·Nada AlbarakatiTaoufik Nedjadi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.