Does Preadmission Cutaneous Chlorhexidine Preparation Reduce Surgical Site Infections After Total Hip Arthroplasty?

Clinical Orthopaedics and Related Research
Bhaveen H KapadiaMichael A Mont

Abstract

Periprosthetic hip infections are among the most catastrophic complications after total hip arthroplasty (THA). We had previously proven that the use of chlorhexidine cloths before surgery may help decrease these infections; hence, we increased the size of the previously reported cohort. (1) Does a preadmission chlorhexidine cloth skin preparation protocol decrease the risk of surgical site infection in patients undergoing THA? (2) When stratified using the National Healthcare Safety Network (NHSN) risk categories, which categories are associated with risk reduction from the preadmission chlorhexidine preparation protocol? Between 2007 and 2013, a group of 998 patients used chlorhexidine cloths before surgery, whereas a group of 2846 patients did not use them and underwent standard perioperative disinfection only. Patient records were reviewed to determine the development of periprosthetic infection in both groups of patients. Patients without the preoperative chlorhexidine gluconate disinfection protocol had a higher risk of infections (infections with protocol: six of 995 [0.6%]; infections in control: 46 of 2846 [1.62%]; relative risk: 2.68 [95% confidence interval {CI}, 1.15-0.26]; p = 0.0226). When stratified based on risk...Continue Reading

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Citations

Jan 17, 2019·The Bone & Joint Journal·V K Alamanda, B D Springer
May 23, 2017·Journal of Bone and Joint Infection·Jaiben GeorgeCarlos A Higuera
Feb 23, 2017·Current Urology Reports·Calvin LeeSandip P Vasavada
Aug 14, 2021·Surgical Infections·Dominique M DockeryDioscaris R Garcia

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