Does preterm birth influence cardiovascular risk in early adulthood?

The Journal of Pediatrics
Gerthe F KerkhofAnita C S Hokken-Koelega

Abstract

To investigate the effect of preterm birth on risk factors for cardiovascular disease (CVD), independent of birth size. Observational study using data of 406 healthy participants aged 18-24 years, from the PROgramming factors for Growth And Metabolism and Prematurity and Small for Gestational Age studies. Associations between gestational age (GA), systolic blood pressure (SBP), diastolic blood pressure (DBP), pulse pressure (PP), blood pressure variability, heart rate (HR), pulse wave velocity, and carotid intima media thickness (cIMT) were studied. To study the differential effects of preterm birth and small birth size for gestational age, these parameters were also analyzed in subgroups born either preterm or term: young adults born small for gestational age with short or normal adult stature, and young adults born appropriate for gestational age with normal adult stature. Subjects born preterm (GA <36 weeks) had higher unadjusted SBP, PP, SBP and DBP variability, and HR, but a lower DBP than subjects born term. GA was inversely associated with SBP, PP, blood pressure variability, and HR, and positively associated with DBP, also after adjustment for confounders. There was no effect of GA on pulse wave velocity and cIMT, a mar...Continue Reading

References

Feb 12, 1999·BMJ : British Medical Journal·J G ErikssonD J Barker
Mar 10, 2000·Pediatric Research·A M FredriksJ M Wit
Jul 21, 2000·Lancet·R J IrvingB R Walker
Oct 19, 2000·Lancet·E Hennessy, E Alberman
Nov 18, 2000·Hypertension·J ErikssonD Barker
Mar 7, 2001·BMJ : British Medical Journal·E O'BrienM G Myers
Mar 5, 2002·Archives of Internal Medicine·Athanase BenetosLouis Guize
Mar 26, 2003·Cardiovascular Drugs and Therapy·Michiel L Bots, D Egbertus Grobbee
Mar 20, 2004·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Ulrich ThollManfred Anlauf
Feb 8, 2006·Circulation·Francesco U S Mattace-RasoJacqueline C M Witteman
Aug 28, 2007·Journal of the American College of Cardiology·Kim FoxUNKNOWN Heart Rate Working Group
Nov 29, 2007·Pediatric Research·Eva KisGyörgy S Reusz
Jan 4, 2008·Journal of Human Hypertension·C L ReltonJ J O'Sullivan
Mar 28, 2008·Acta Paediatrica·Anna-Karin Edstedt BonamyMikael Norman
Nov 18, 2008·Early Human Development·Kari Anne Indredavik EvensenTorstein Vik
Mar 7, 2009·Stroke; a Journal of Cerebral Circulation·Olli T RaitakariJorma S A Viikari
Jun 6, 2009·JAMA : the Journal of the American Medical Association·Ralph W J LeunissenAnita Hokken-Koelega
Oct 20, 2009·The Journal of Clinical Endocrinology and Metabolism·Gerthe F KerkhofAnita C S Hokken-Koelega
Dec 17, 2009·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Mandy G Keijzer-VeenBert J van der Heijden
May 25, 2010·Seminars in Perinatology·Mikael Norman
Dec 14, 2011·Hypertension·Barbara T Alexander, Suttira Intapad

❮ Previous
Next ❯

Citations

Jun 27, 2014·Journal of Obstetrics and Gynaecology of India·Sarit AvrahamDaniel Seidman
Dec 3, 2014·Clinics in Perinatology·Robert H Lane
Mar 13, 2014·Current Problems in Pediatric and Adolescent Health Care·Roya Kelishadi, Parinaz Poursafa
Jan 23, 2016·Revista chilena de pediatría·M Angélica González StägerAna San Martín Navarrete
Sep 25, 2015·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Henry BoardmanPaul Leeson
Dec 17, 2015·Cardiovascular Ultrasound·Baoge Qu, Tao Qu
May 26, 2015·Clinica Chimica Acta; International Journal of Clinical Chemistry·Pier Paolo BassareoGiuseppe Mercuro
Sep 26, 2012·Diabetes/metabolism Research and Reviews·Danila BeneventoMarco Cappa
Mar 1, 2014·Arthritis & Rheumatology·Florentien D O de SteenwinkelRadboud J E M Dolhain
Dec 1, 2012·Cholesterol·Roya KelishadiSamuel S Gidding
Jul 11, 2013·Journal of Environmental and Public Health·Roya KelishadiFahimeh Jamshidi
Jan 11, 2014·Annual Review of Psychology·Marc H Bornstein
Apr 12, 2014·Pain Research and Treatment·Mélanie MorinSylvie Lafrenaye
Mar 19, 2013·Autonomic Neuroscience : Basic & Clinical·Alfredo J GarciaJan-Marino Ramirez
Jul 13, 2012·The Journal of Pediatrics·Samuel S Gidding
Dec 1, 2015·PloS One·Carolina C J SmeetsAnita C S Hokken-Koelega
Nov 4, 2016·Nature Reviews. Endocrinology·Veronica MericqAnita Hokken-Koelega
Sep 11, 2016·The Journal of Endocrinology·Baiba Steinbrekera, Robert Roghair
Mar 28, 2018·Pediatric Research·Heidi M Harmon, Tamara S Hannon
Oct 28, 2016·Arteriosclerosis, Thrombosis, and Vascular Biology·Irena Odri KomazecUrsula Kiechl-Kohlendorfer
Apr 11, 2019·Journal of the American Heart Association·Anna PosodUrsula Kiechl-Kohlendorfer
Jul 3, 2019·Journal of Perinatology : Official Journal of the California Perinatal Association·Luc P BrionMaria Caraig
May 22, 2020·The Journal of Clinical Endocrinology and Metabolism·Wesley J GoedegebuureAnita C S Hokken-Koelega
Aug 28, 2020·Arteriosclerosis, Thrombosis, and Vascular Biology·Adrien FlahaultAnne Monique Nuyt
Jul 28, 2020·International Journal of Molecular Sciences·Elena SpadaDavide Gentilini
Jul 10, 2018·Clinical Epigenetics·Qihua TanLene Christiansen
Nov 27, 2018·Archives of Gynecology and Obstetrics·Liron BerkmanGali Pariente
Dec 2, 2020·International Journal of Environmental Research and Public Health·Carol J MillerBridget B Baker
Jan 12, 2021·Frontiers in Public Health·Anna PerezDominique Singer
Jan 15, 2021·Scientific Reports·Giovanna de Paula VidigalVitor E Valenti

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.