Does probability guided hysteroscopy reduce costs in women investigated for postmenopausal bleeding?

TheScientificWorldJournal
M C BreijerA Timmermans

Abstract

To evaluate whether a model to predict a failed endometrial biopsy in women with postmenopausal bleeding (PMB) and a thickened endometrium can reduce costs without compromising diagnostic accuracy. Model based cost-minimization analysis. A decision analytic model was designed to compare two diagnostic strategies for women with PMB: (I) attempting office endometrial biopsy and performing outpatient hysteroscopy after failed biopsy and (II) predicted probability of a failed endometrial biopsy based on patient characteristics to guide the decision for endometrial biopsy or immediate hysteroscopy. Robustness of assumptions regarding costs was evaluated in sensitivity analyses. Costs for the different strategies. At different cut-offs for the predicted probability of failure of an endometrial biopsy, strategy I was generally less expensive than strategy II. The costs for strategy I were always € 460; the costs for strategy II varied between € 457 and € 475. At a 65% cut-off, a possible saving of € 3 per woman could be achieved. Individualizing the decision to perform an endometrial biopsy or immediate hysteroscopy in women presenting with postmenopausal bleeding based on patient characteristics does not increase the efficiency of th...Continue Reading

References

May 1, 1996·Acta Obstetricia Et Gynecologica Scandinavica·J K GuptaC Hau
Nov 11, 1998·JAMA : the Journal of the American Medical Association·R Smith-BindmanD Grady
Apr 1, 1999·The Australian & New Zealand Journal of Obstetrics & Gynaecology·S J Gordon, J Westgate
Oct 6, 2001·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·R B GoldsteinJ Walker
Apr 13, 2002·BJOG : an International Journal of Obstetrics and Gynaecology·T Justin ClarkJanesh K Gupta
Dec 18, 2003·Acta Obstetricia Et Gynecologica Scandinavica·Elisabeth Epstein
Apr 28, 2006·BJOG : an International Journal of Obstetrics and Gynaecology·T J ClarkK S Khan
Sep 25, 2007·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·H C van DoornUNKNOWN Dutch Study in Postmenopausal Bleeding (DUPOMEB)
Jul 25, 2008·BJOG : an International Journal of Obstetrics and Gynaecology·A R W WilliamsH O D Critchley
Jan 22, 2009·Obstetrics and Gynecology·UNKNOWN American College of Obstetricians and Gynecologists
Jul 3, 2013·Acta Obstetricia Et Gynecologica Scandinavica·Nicole C M VisserJohanna M A Pijnenborg

❮ Previous
Next ❯

Citations

Apr 6, 2017·Journal of Korean Medical Science·Min Kyoung KimSeok Kyo Seo

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy
biopsies

Software Mentioned

TreeAge
TreeAgePro

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.