PMID: 15338801Sep 2, 2004Paper

Does respiratory syncytial virus subtype influences the severity of acute bronchiolitis in hospitalized infants?

Respiratory Medicine
Nikolaos G PapadopoulosDimitrios Kafetzis

Abstract

Respiratory syncytial virus (RSV) subtypes A and B are present either simultaneously or alternate during yearly epidemics. It is still not clear whether clinical severity of acute bronchiolitis differs between the two subtypes. Reverse transcription polymerase chain reaction was used to subtype RSV in previously healthy infants hospitalized with RSV bronchiolitis during a winter epidemic. A severity index based on heart rate, respiratory rate, wheezing, difficulty in feeding and oxygen saturation was calculated upon admission. Infants infected with RSV subtype-A were found to have a significantly higher (more severe) clinical score than those infected with RSV-B. There was no statistically significant difference in duration of hospitalization or need of intensive care. Boys and infants younger than 3 months of age were also more severely affected than girls or older infants, respectively. These results support the notion that RSV-A-induced bronchiolitis is more severe than RSV-B-induced one, in agreement with the majority of previously published studies.

References

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Citations

Aug 27, 2013·Early Human Development·A NicolaiF Midulla
Jun 8, 2011·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·W Sánchez-YebraUNKNOWN LRTI Research Group
Oct 13, 2015·Expert Review of Respiratory Medicine·Haben Y AbrahaBosco Paes
Aug 30, 2012·Clinics in Chest Medicine·Gaetano CaramoriAlberto Papi
Feb 16, 2010·Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)·C Ochoa SangradorUNKNOWN Grupo de Revisión del Proyecto aBREVIADo (BRonquiolitis-Estudio de Variabilidad, Idoneidad y ADecuación)
Oct 31, 2012·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Laura HatzlerNikolaos G Papadopoulos
Mar 26, 2011·Pediatric Pulmonology·Melvin Wright, Giovanni Piedimonte
Jun 5, 2007·Respiratory Medicine·Matthew E FalagasKonstantinos Z Vardakas
Jul 20, 2016·American Journal of Infection Control·Sean G KellyTeresa R Zembower
May 2, 2017·Journal of Medical Virology·Mahima SahuPradip V Barde
Feb 2, 2010·Paediatric Respiratory Reviews·Claire Wainwright
Apr 7, 2017·The Pediatric Infectious Disease Journal·Federico R LahamCarlos A Camargo
Aug 8, 2017·International Journal of Molecular Sciences·Silvia VandiniMarcello Lanari
Nov 28, 2017·Allergy, Asthma & Immunology Research·Chang Keun KimJames E Gern
Oct 19, 2017·The Journal of Infectious Diseases·Rosa Rodriguez-FernandezAsuncion Mejias
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Jul 15, 2021·The Pediatric Infectious Disease Journal·Ahmad YanisNatasha B Halasa
Apr 30, 2020·Intervirology·Katerina TsergouliAnna Papa

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