Does the historical literature on encephalitis lethargica support a simple (direct) relationship with postencephalitic Parkinsonism?

Movement Disorders : Official Journal of the Movement Disorder Society
Joel A VilenskySherman McCall

Abstract

This article and the subsequent one suggest that the currently accepted view of a simplistic (direct) relationship between encephalitis lethargica (EL) and postencephalitic Parkinsonism (PEP) is based on a incomplete evaluation of the epidemic period literature. In this article we provide a detailed analysis of the literature from the period that demonstrates that Parkinsonism was not initially part of acute EL symptomatology, that PEP was not typically the prevailing type of chronic EL and that oculogyric crises were never part of acute EL symptomatology and not initially associated with PEP. The second paper uses these finding, and also examines the clinical justifications for concluding that all patients with PEP had prior acute episodes of EL, to reevaluate the presumed direct etiologic relationship between EL and PEP.

References

Feb 1, 1987·Brain : a Journal of Neurology·R S Howard, A J Lees
Aug 1, 1981·Journal of Neurology, Neurosurgery, and Psychiatry·D RailM Swash
May 1, 1997·Movement Disorders : Official Journal of the Movement Disorder Society·S B BluntG D Perkin
Nov 26, 1997·Journal of the Royal Society of Medicine·R R Dourmashkin
Apr 22, 1999·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·I LitvanY Agid
Jul 11, 2001·Journal of Neuropathology and Experimental Neurology·A H ReidJ K Taubenberger
Oct 27, 2001·Archives of Neurology·M S Dickman
Mar 1, 1965·Archives of Neurology·R C DUVOISIN, M D YAHR
Mar 15, 1965·JAMA : the Journal of the American Medical Association·W D BOWMAN
Oct 23, 2003·Brain : a Journal of Neurology·Russell C DaleGavin Giovannoni
May 5, 2009·Journal of Neurology·Robert Lopez-AlberolaSpyridon Papapetropoulos
Nov 1, 1927·Proceedings of the Royal Society of Medicine·E Bramwell
Oct 26, 1918·British Medical Journal·A J Hall
Mar 24, 1923·British Medical Journal

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Citations

Feb 18, 2011·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Joel A VilenskySid Gilman
Aug 19, 2014·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Dennis Tappe, David E Alquezar-Planas
Jul 2, 2015·Neurosurgical Focus·Lillian B BoettcherMichael E Sughrue
Feb 6, 2017·Parkinsonism & Related Disorders·Johanna C M SchilderPeter J Koehler
Aug 11, 2020·Current Tropical Medicine Reports·Amy Y VittorSteven T DeKosky
Sep 2, 2017·Journal of the History of the Neurosciences·Nicolaas J M Arts
Jul 10, 2021·Journal of the History of the Neurosciences·Olivier Walusinski

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