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Does the human placenta delivered at term have a microbiota? Results of cultivation, quantitative real-time PCR, 16S rRNA gene sequencing, and metagenomics

American Journal of Obstetrics and Gynecology

Mar 6, 2019

Kevin R TheisSonia S Hassan

Abstract

The human placenta has been traditionally viewed as sterile, and microbial invasion of this organ has been associated with adverse pregnancy outcomes. Yet, recent studies that utilized sequencing techniques reported that the human placenta at term contains a unique microbiota. These con...read more

Mentioned in this Paper

Prevalence Studies
DNA Contamination
Study
Postcesarean Section
Environment
Kinetic Polymerase Chain Reaction
Placenta
Laboratory
Genetic Markers
Organ
139
1
2
80
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Does the human placenta delivered at term have a microbiota? Results of cultivation, quantitative real-time PCR, 16S rRNA gene sequencing, and metagenomics

American Journal of Obstetrics and Gynecology

Mar 6, 2019

Kevin R TheisSonia S Hassan

PMID: 30832984

DOI: 10.1016/j.ajog.2018.10.018

Abstract

The human placenta has been traditionally viewed as sterile, and microbial invasion of this organ has been associated with adverse pregnancy outcomes. Yet, recent studies that utilized sequencing techniques reported that the human placenta at term contains a unique microbiota. These con...read more

Mentioned in this Paper

Prevalence Studies
DNA Contamination
Study
Postcesarean Section
Environment
Kinetic Polymerase Chain Reaction
Placenta
Laboratory
Genetic Markers
Organ
139
1
2
80

Similar Papers Found In These Feeds

Maternal-fetal Interface

The maternal-fetal interface encompasses the decidua from the mother and the placenta from the developing fetus. Throughout pregnancy important cells and receptors are located on the interface. Cells including fetal trophoblasts and toll-like receptors are of great importance. Here is the latest research on the maternal-fetal interface.

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  • References
  • Citations7
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    References currently unavailable

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  • References
  • Citations7
1
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