Does the location of thrombosis determine the risk of disease recurrence in patients with proximal deep vein thrombosis?

The American Journal of Medicine
J D DouketisJ S Ginsberg

Abstract

To determine if the location of deep vein thrombosis is a predictor of recurrent venous thromboembolism during the initial 3 months of anticoagulant therapy. The study population consisted of 1,149 consecutive patients with symptomatic proximal deep vein thrombosis. In all patients, deep vein thrombosis was confirmed by Duplex ultrasound or venography and was classified as popliteal, femoral, or iliofemoral. Patients received initial treatment with unfractionated heparin, enoxaparin, or reviparin for least 4 days, as well as a coumarin derivative, with a target international normalized ratio of 2.0 to 3.0, starting on the 1st or 2nd day of treatment. All patients were followed for 3 months, and all episodes of recurrent venous thromboembolism were confirmed with objective diagnostic tests. The overall rate of recurrent venous thromboembolism during the initial 3 months of anticoagulant therapy was 5.5% (63/1,149). The rate of recurrence in patients with popliteal vein thrombosis was 5.1% (23/453); in patients with femoral vein thrombosis, it was 5.3% (34/645); and in patients with iliofemoral vein thrombosis, it was 11.8% (6/51). Two clinical risk factors were associated with an increased risk of recurrent venous thromboembolis...Continue Reading

References

Oct 15, 1992·The New England Journal of Medicine·P PrandoniJ W ten Cate
Mar 11, 1992·Archives of Surgery·A MarkelD E Strandness
Oct 1, 1993·Annals of Medicine·P Prandoni
Jul 1, 1993·Journal of Internal Medicine·M HeldalU Abildgaard
Jul 1, 1996·Annals of Internal Medicine·P PrandoniM H Prins
Oct 1, 1996·AJR. American Journal of Roentgenology·J P LaissyE Schouman-Claeys
Sep 4, 1997·The New England Journal of Medicine·UNKNOWN Columbus InvestigatorsR Baildon
Feb 18, 1998·JAMA : the Journal of the American Medical Association·J D DouketisJ S Ginsberg
Nov 20, 1998·Chest·T M HyersV Tapson
Dec 11, 1999·JAMA : the Journal of the American Medical Association·M K Horne, R Chang
Mar 29, 2000·Archives of Internal Medicine·P O HanssonH Eriksson

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Citations

Sep 17, 2013·Annales de cardiologie et d'angéiologie·R Ben SalahZ Bahloul
Jul 9, 2014·Journal of Vascular and Interventional Radiology : JVIR·Suresh VedanthamUNKNOWN Society of Interventional Radiology and Cardiovascular and Interventional Radiological Society of Europe Standards of Practi
May 25, 2012·International Journal of Critical Illness and Injury Science·Sanjith Saseedharan, Sunil Bhargava
Mar 2, 2013·Seminars in Interventional Radiology·Seth J Klein, Suresh Vedantham
Feb 18, 2011·Journal of Thrombosis and Thrombolysis·Marco P Donadini, Walter Ageno
Feb 19, 2002·Journal of the American College of Surgeons·G Patrick Clagett
Dec 14, 2011·Hematology·Suresh Vedantham
May 21, 2014·Techniques in Vascular and Interventional Radiology·Suresh Vedantham
Jan 19, 2016·Journal of Thrombosis and Thrombolysis·John A HeitRichard H White
Jan 19, 2016·Journal of Thrombosis and Thrombolysis·Suresh VedanthamNeil A Goldenberg
Jun 16, 2012·Journal of Vascular and Interventional Radiology : JVIR·Andrew K KurklinskyPeter Gloviczki
Oct 29, 2011·Mayo Clinic Proceedings·Benjamin Kloesel, Roger F J Shepherd
Jul 5, 2011·Progress in Cardiovascular Diseases·J Stephen Jenkins
Sep 10, 2010·Seminars in Vascular Surgery·Anthony J Comerota
Mar 29, 2006·Journal of Vascular and Interventional Radiology : JVIR·Suresh VedanthamUNKNOWN Technology Assessment Committe of the Society of Interventional Radiology
Mar 29, 2006·Journal of Vascular and Interventional Radiology : JVIR·Suresh VedanthamDavid Sacks
Apr 15, 2006·Journal of Vascular and Interventional Radiology : JVIR·Suresh VedanthamUNKNOWN Society of Interventional Radiology
Mar 2, 2010·Journal of the American Medical Directors Association·Barbara J ZarowitzArthur Wheeler
Nov 8, 2015·Japanese Journal of Clinical Oncology·Soichiro IkushimaKeisuke Kondo
Jul 9, 2009·Journal of Vascular and Interventional Radiology : JVIR·Suresh VedanthamUNKNOWN CIRSE and SIR Standards of Practice Committees
Jul 9, 2009·Journal of Vascular and Interventional Radiology : JVIR·Suresh VedanthamUNKNOWN Technology Assessment Committee of the Society of Interventional Radiology
Feb 26, 2008·Journal of Vascular and Interventional Radiology : JVIR·Hyun S KimMichael B Streiff
Aug 24, 2006·Journal of Vascular Surgery·Javier Trujillo-SantosUNKNOWN RIETE Investigators
Mar 6, 2012·American Journal of Hematology·Suresh Vedantham
May 23, 2013·The British Journal of Surgery·J H SaundersN Altaf
Jul 17, 2013·Journal of Thrombosis and Haemostasis : JTH·S C Cannegieter, A van Hylckama Vlieg
Jul 17, 2013·Journal of Thrombosis and Haemostasis : JTH·W AgenoA Squizzato
Feb 26, 2013·Journal of Thrombosis and Haemostasis : JTH·M J BaldwinA H Davies
May 28, 2010·The Mount Sinai Journal of Medicine, New York·Robert A Lookstein, Christopher F Giordano
Jul 16, 2010·The British Journal of Surgery·N LabropoulosM Meissner
Aug 2, 2006·Thrombosis Research·Matthew T RondinaGeorge M Rodgers
Mar 6, 2003·Journal of Vascular Surgery·Barbara Borst-KrafekAndreas Steiner
May 10, 2001·The American Journal of Medicine·M K Horne
Apr 22, 2015·British Journal of Haematology·Kathryn J LangRoopen Arya
Jul 8, 2015·Journal of Thrombosis and Haemostasis : JTH·S Vedantham
Jun 14, 2013·International Journal of Vascular Medicine·Anat Rabinovich, Susan R Kahn
Jun 17, 2015·Nature Reviews. Cardiology·John A Heit
Nov 6, 2007·Journal of Vascular Surgery·Anthony J Comerota, Marilyn H Gravett
Jun 3, 2008·Journal of Vascular Surgery·Nicos LabropoulosPeter J Pappas

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