Does the nanometre scale topography of titanium influence protein adsorption and cell proliferation?

Colloids and Surfaces. B, Biointerfaces
Kaiyong CaiKlaus D Jandt

Abstract

To investigate the influence of titanium films with nanometre scale topography on protein adsorption and cell growth, three different model titanium films were utilized in the present study. The chemical compositions, surface topographies and wettability were investigated by using X-ray photoelectron spectroscopy (XPS), atomic force microscopy (AFM) and water contact angle measurement, respectively. The films share the same surface chemistry but exhibit different topographies on a nanometre scale. Thus, they act as model systems for biological studies regarding surface topography effects. The films were obtained by varying the deposition rate and the film thickness, respectively. These films displayed nanometre scale surface roughness (root mean square roughness, R(rms)) from 2 to 21 nm over areas of 50 microm x 50 microm, with different grain sizes at their surfaces. Albumin and fibrinogen adsorption on these model titanium films were performed in this study. Bicinchoninic acid assay was employed to determine the amount of adsorbed protein on titanium film surfaces. No statistically significant differences, however, were observed for either albumin or fibrinogen adsorption between the different groups of titanium films. No sta...Continue Reading

References

Jun 5, 1998·Biomaterials·A Curtis, C Wilkinson
Dec 16, 1998·Journal of Colloid and Interface Science· van der Mei HCH J Busscher
Jul 28, 2004·Biomaterials·Annette DienerJoachim Rychly
Mar 2, 2005·Tissue Engineering·Cameron J WilsonMark J Pearcy

❮ Previous
Next ❯

Citations

Jul 11, 2007·Journal of Materials Science. Materials in Medicine·Taik Nam KimB B Panigrahi
Dec 25, 2007·Journal of Materials Science. Materials in Medicine·E A dos SantosK Anselme
Jul 2, 2008·Journal of Materials Science. Materials in Medicine·Jie HeWantao Chen
May 26, 2009·Journal of Materials Science. Materials in Medicine·Animesh ChoubeyEugene A Sprague
Feb 3, 2011·Journal of Materials Science. Materials in Medicine·Huanjun ZhouChangsheng Liu
Aug 13, 2011·Journal of Materials Science. Materials in Medicine·Tingting ZhaoTao Zhang
May 21, 2013·Biofouling·Cindy Goes DodoAltair Antoninha Del Bel Cury
May 22, 2013·Tissue Engineering. Part a·Mark A BirchMasatsugu Shimomura
Jul 19, 2013·Journal of Biomedical Nanotechnology·D M Rivera-ChaconJ E Ramirez-Vick
Aug 6, 2010·PloS One·Pasquale Emanuele ScopellitiPaolo Milani
Aug 26, 2010·Nanomedicine·Sandrine LavenusPierre Layrolle
Sep 8, 2012·Biointerphases·Jana SommerfeldCarsten Ronning
Jan 1, 2014·Dental Materials : Official Publication of the Academy of Dental Materials·M S WalterH J Haugen
Aug 25, 2007·Nanomedicine·Ganesan Balasundaram, Thomas J Webster
Apr 17, 2008·The Journal of Chemical Physics·Sylvain ClairDmitrii F Perepichka
Jul 27, 2014·Materials Science & Engineering. C, Materials for Biological Applications·Xiu-Mei LiJian Xu
Sep 26, 2015·International Journal of Molecular Sciences·Weiwei LouGang Wu
Mar 10, 2016·Materials Science & Engineering. C, Materials for Biological Applications·E SalahinejadL Tayebi
Jun 29, 2015·Materials Science & Engineering. C, Materials for Biological Applications·Chao ZhangXinhua Sun
Jun 19, 2012·Advanced Drug Delivery Reviews·Peter KoeglerPeter Kingshott
Sep 3, 2010·Acta Biomaterialia·Miguel Padial-MolinaPedro J Ramón-Torregrosa
Aug 3, 2010·Colloids and Surfaces. B, Biointerfaces·Roya DastjerdiShadi Shahsavan
Feb 23, 2010·Colloids and Surfaces. B, Biointerfaces·Cristèle J NonckremanChristine C Dupont-Gillain
Feb 23, 2010·Colloids and Surfaces. B, Biointerfaces·Jun ZhengHong Chen
Jan 30, 2010·Materials Science & Engineering. C, Materials for Biological Applications·Jennifer L WehmeyerCarlos D García
Sep 12, 2015·Materials Science & Engineering. C, Materials for Biological Applications·Argelia Almaguer-FloresSandra E Rodil
Aug 8, 2015·Materials Science & Engineering. C, Materials for Biological Applications·Jing PengXianjin Yang
Jul 12, 2008·Biomaterials·Gustavo MendonçaLyndon F Cooper
Jul 1, 2008·Colloids and Surfaces. B, Biointerfaces·A Dolatshahi-PirouzF Besenbacher
Dec 25, 2007·Biomaterials·Fabio VariolaAntonio Nanci
Jun 19, 2013·Journal of Biomedical Materials Research. Part a·C NuneL P Karjalainen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.