Does the sex ratio of singleton births after frozen single blastocyst transfer differ in relation to blastocyst development?

Reproductive Biology and Endocrinology : RB&E
Hua LouShihong Cui

Abstract

To investigate the associations between blastocyst development and the sex ratio (male:female) among singleton live births resulting from single-blastocyst frozen embryo transfer (FET) cycles. Patients with singleton live births following the first autologous single FET of non- preimplantation genetic testing (PGT) blastocysts in a single reproductive medicine department between January 2015 and February 2019 were included in this retrospective study. The primary outcome measure was the singleton sex ratio. Multivariable logistic regression models were used to estimate the associations between blastocyst quality and singleton sex ratio after adjustment for some potential confounders. There were 638 high-quality and 572 poor-quality single blastocyst FETs, and the blastocysts were conceived via 855 IVF and 355 ICSI treatments. A total of 1210 singleton live births were assessed. High-quality single blastocyst FET resulted in a significantly higher sex ratio than did poor-quality single blastocyst FET (60% vs. 49.7%, P < 0.001). The infertility cause was not associated with sex ratio among singleton live births (P = 0.537). The results of a multivariate analysis revealed that a high-quality blastocyst has a 150% higher probabilit...Continue Reading

References

Dec 22, 1999·Human Reproduction·R JacobsenA Mouritsen
Jun 17, 2000·Fertility and Sterility·D K GardnerW B Schoolcraft
Jan 17, 2002·The New England Journal of Medicine·E R NorwitzS J Fisher
Apr 5, 2003·Reproductive Biomedicine Online·Tetsunori MukaidaMagosaburo Kasai
Nov 23, 2006·Fertility and Sterility·Martha LunaJason Barritt
Apr 29, 2008·Fertility and Sterility·Mamdoh EskandarSaria E Y Mohmad
Sep 5, 2009·Journal of Assisted Reproduction and Genetics·Martha Agnes HentemannKjell Bertheussen
Jun 12, 2010·Fertility and Sterility·Samer AlfarawatiDagan Wells
Sep 25, 2010·Fertility and Sterility·Jason C ParksMandy G Katz-Jaffe
Jan 28, 2012·Fertility and Sterility·Dhanushi FernandoDavid Lindsay Healy
Aug 1, 2012·Journal of Assisted Reproduction and Genetics·Eman Elgindy, Mervat Sheikh-El-Arab Elsedeek
Mar 5, 2013·Fertility and Sterility·Marissa L SteinbergDenise J Jamieson
Jun 19, 2013·Reproductive Biomedicine Online·Lixia ZhuLei Jin
Dec 17, 2014·Fertility and Sterility·Frederick LicciardiDavid H McCulloh
Jul 21, 2015·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Hua ChenHong-Shan Ge
Dec 18, 2015·Reproductive Biomedicine Online·Abha MaheshwariSiladitya Bhattacharya
Sep 15, 2016·Human Fertility : Journal of the British Fertility Society·Jessica SubiraMuhammad Fatum
Jan 11, 2017·Fertility and Sterility·Mohamad IraniZev Rosenwaks
Mar 16, 2017·Fertility and Sterility·UNKNOWN Practice Committee of the American Society for Reproductive Medicine. Electronic address: ASRM@asrm.orgMichael Vernon
Feb 24, 2019·Reproductive Biology and Endocrinology : RB&E·Hiromitsu HattoriUNKNOWN Japan Environment and Children’s Study Group

❮ Previous
Next ❯

Citations

Jun 5, 2021·Journal of Assisted Reproduction and Genetics·Christopher P MoutosJohn R Crochet

❮ Previous
Next ❯

Methods Mentioned

BETA
hormone replacement therapy

Software Mentioned

SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.