PMID: 18431831Apr 24, 2008Paper

Does the strength of the association between foetal growth rate and ischaemic heart disease mortality differ by social circumstances in early or later life?

Journal of Epidemiology and Community Health
K RajaleidIlona Koupil

Abstract

To study whether the effect of size at birth on the risk of ischaemic heart disease (IHD) death is modified by social circumstances in childhood or in adulthood. A cohort study. Data on circumstances at birth were retrieved from archived obstetric records, social characteristics in adulthood and mortality follow-up through routine registers. 6159 men and 5663 women who were born in Uppsala University Hospital, Sweden (the Uppsala Birth Cohort) during 1915-1929, were singleton births with more than 30 weeks of gestational age and were alive in 1961. Follow-up time 1961-2002 (from age 31-46 to 73-88 years). Death from IHD. Multivariate Cox regression with age as the time scale, controlling for year of birth and stratified by gender. The risk of IHD death was lower among men and women with higher weight for gestational age. Lower social class in adulthood was associated with a higher risk of IHD death. The effect of size at birth on IHD mortality did not appear to be modified by social class at birth but was only present in men of higher social class in adulthood (hazard ratio per 1 SD weight for gestational age 0.84, 95% CI 0.75 to 0.93). Weight for gestational age was inversely associated with the risk of IHD death in men and wo...Continue Reading

Citations

Jun 1, 2013·Cancer Causes & Control : CCC·Ulla SovioIlona Koupil
Aug 14, 2012·Paediatric and Perinatal Epidemiology·Ulla SovioIlona Koupil
Apr 12, 2014·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Liisa BybergIlona Koupil
Mar 7, 2014·Social Science & Medicine·Tim A BrucknerRalph A Catalano
Aug 25, 2009·Scandinavian Journal of Public Health·Kristna RajaleidIlona Koupil
May 4, 2016·Journal of Developmental Origins of Health and Disease·S JuárezI Koupil
Feb 1, 2021·The Journal of Pediatrics·Lindsay R PoolNorrina B Allen

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