Does using applied muscle tension at strategic time points during donation reduce phlebotomist- and donor-reported vasovagal reaction rates? A three-armed randomized controlled trial

Transfusion
A ThijsenB Masser

Abstract

Vasovagal reactions (VVRs) have a negative impact on donor safety and return. Applied muscle tension (AMT) increases blood pressure temporarily and has been suggested as a way to reduce donors' risk of VVRs. This study evaluated whether using AMT at three different time points during the donation procedure reduces the VVR symptoms reported by donors and the VVR reactions recorded by phlebotomists. A three-arm, multicenter, open-label randomized controlled trial was used to compare VVR symptoms and reaction rates between those practicing AMT during the entire donation (n = 244) to practicing AMT at VVR high-risk time points (n = 250) to a standard blood donation control group (n = 240). All participants were asked to drink 500 mL of water in the waiting area, and an even distribution of new and repeat donors was sought across conditions. Across all conditions, donors reported few VVR symptoms and the rate of reporting did not differ significantly across conditions. However, donors who practiced AMT at strategic time points had a significantly lower number of phlebotomist-registered VVRs in comparison to the other two study groups, with these rates not varying by sex or donor status. Greater compliance by donors with AMT instruct...Continue Reading

References

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Apr 28, 2012·Transfusion·Anne F EderRoger Y Dodd
Mar 3, 2015·Journal of Anxiety Disorders·Philippe T GilchristBlaine Ditto
Nov 18, 2017·Transfusion Medicine·A Thijsen, B Masser

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Citations

Apr 9, 2019·Prehospital Emergency Care : Official Journal of the National Association of EMS Physicians and the National Association of State EMS Directors·Jan L JensenUNKNOWN First Aid and Pediatric Task Forces of the International Liaison Committee on Resuscitation
Jun 20, 2019·Psychology & Health·Eamonn FergusonRonan E O'Carroll
Jun 19, 2021·Transfusion·Susan N Rossmann, Beth A Hartwell

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