Dog allergen immunotherapy: past, present, and future

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
Derek M Smith, Christopher A Coop

Abstract

To review the published medical literature on dog allergy immunotherapy and discuss prior clinical trials, important allergens, extract specifics, and potential future treatment options for dog allergy relevant to the clinical allergist. MEDLINE search was performed using the terms dog, immunotherapy, and allergy limited to human studies from any period. Articles cited in selected studies also were reviewed for appropriateness of inclusion into this review. Publications were included that were original research and fit the topic of dog allergen immunotherapy, specifically articles that investigated prior effectiveness and safety of dog allergen immunotherapy, dog extracts, identification of dog allergens, and current prescribing trends among allergists. Two hundred fifteen articles were initially identified and 60 were reviewed in complete detail for inclusion in this review. The primary focus was placed on the 17 clinical trials that investigated the safety and efficacy of dog immunotherapy and the 19 studies that explored and defined the complex allergenic profile of dog extracts. The medical literature on the use of dog extract immunotherapy in patients with hypersensitivity to dog shows poor and conflicting results of clini...Continue Reading

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Citations

Jun 7, 2016·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Gennaro LiccardiPaola Rogliani
Jun 7, 2016·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Derek Smith, Christopher A Coop
May 10, 2017·International Journal of Environmental Research and Public Health·Anne M ForemanOliver Wirth
Jan 11, 2018·Allergy·I DávilaM Torrecillas
Feb 8, 2018·Allergy, Asthma & Immunology Research·Sanny K Chan, Donald Y M Leung
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May 19, 2020·The Journal of Allergy and Clinical Immunology. in Practice·Moisés A CalderonHendrik Nolte
Feb 6, 2020·International Archives of Allergy and Immunology·Martina VachováPetra Vítovcová

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